Ticiana Leal, MD, is at the forefront of an intriguing and evolving discussion centered on the mechanism underlying tumor treating fields (TT fields). These fields are a topic of great interest in the field of oncology, and Dr. Leal's expertise shines through as she delves into the question at hand: how do tumor-treating fields actually work?
TT fields, a novel approach in cancer therapy, harness the power of electric fields to interact with electrically charged components within the human body, specifically targeting dividing cancer cells. Their precise mode of action revolves around disrupting the crucial process of mitosis, where cells divide and multiply. Dr. Leal and her colleagues explore this disruption in-depth, unraveling the intricate cellular events it triggers.
One key aspect they investigate is the induction of ploidy, an intriguing phenomenon where cells accumulate multiple sets of chromosomes due to TT field interference. This shift in cellular dynamics raises intriguing questions about the potential impact on cancer cell survival and behavior.