This educational activity features a panel consisting of an oncologist as well as leading experts (a urologist and a researcher) in prostate cancer care considerations in gay and bisexual men (GBM). This panel discusses quality of life considerations and disparities among GBM with prostate cancer. The panel’s aim is to provide clinicians with real-world strategies to facilitate optimal communication and shared decision-making with these patients. This initiative also provides the latest epidemiological and clinical data, controversies, and evolving treatment practices to improve patient-reported outcomes. Additionally, a gay patient shares his prostate cancer story and perspectives to better illustrate and help address the unmet needs that exist among the GBM population. Clinicians need to know the resources out there for GBM with prostate cancer as this minority population is often not focused on in medical education.