IMPACT, the UKs first large-scale clinical trials platform for patients receiving a stem cell transplant, is launching in 2018. Here, Charles Craddock, CBE, FRCP (UK), FRCPath, DPhil, of the University of Birmingham, Birmingham, UK, discusses plans for the first year of IMPACT, with four prospective randomized trials set to be launched. Prof. Craddock covers the trials and rationale behind them, including COSI and PRO-DLI, which is the first randomized study investigating the benefit of donor lymphocytic infusions for the prevention of relapse post-HSCT in patients with high-risk myeloid malignancy. This video was recorded at the 2018 British Society for Hematology (BSH) Annual Scientific Meeting in Liverpool, UK.
UK transplantation trials network: four IMPACT trials launching in 2018
