Barbara Eichhorst, MD from University of Cologne, Cologne, Germany discusses using venetoclax in the treatment of patients with chronic lymphocytic leukemia (CLL). Venetoclax will be approved for high risk CLL patients with 17p deletions, and has received good results in studies. Furthermore it has performed well in contrast with ibrutinib or idelalisib, as complete responses (CR) and minimal residual disease (MRD) negativity in relapsed/refractory CLL has been reported – even in monotherapy. Dr Eichhorst also discusses combinations with the CD20 antibody. Recorded at the European Hematology Association (EHA) 2016 Annual Congress in Copenhagen, Denmark.
Treating CLL with venetoclax
