Immunotherapies can induce a range of common, as well as rare, side effects. These may be difficult for healthcare professionals to spot if they have not observed them previously. In this interview, Liz Gifford of the University Hospital Southampton NHS Foundation Trust, Southampton, UK, discusses some of the rarer toxicities that can be seen in cancer patients. This video was recorded at the UK Oncology Nursing Society (UKONS) Annual Conference 2017 in Harrogate, UK.