In this video, Oliver Ottmann, MD, FRCPath, of Cardiff University, Cardiff, UK, discusses the importance of allogeneic transplant in different populations of patients with Ph-positive acute lymphoblastic leukemia (ALL). From the 2018 European School of Hematology (ESH) Clinical Updates on Acute Leukemias, held in Budapest, Hungary, Prof. Ottmann also emphasizes the areas for improvement in measurable residual disease (MRD) testing.