An advanced age can limit treatment options when tackling leukemia. Speaking from the International Conference on Acute Myeloid Leukaemia 2017, Estoril, Portugal by the European School of Hematology (ESH), Prof. John DiPersio, MD, PhD of Washington University School of Medicine, Washington, WA discusses treatment options for patients with leukemia who are over the age of 60, and the future applications of chemotherapy and bispecifics in this group.