The scientific advances reported at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, were extraordinary. This years meeting saw first-time attempts at integrating multiple levels of biological data analysis, including genomics, epigenetics and immunological profiling, which were exciting from both a biological and clinical standpoint. Speaking from the meeting, Kenneth Anderson, MD, of the Dana-Farber Cancer Institute, Boston, MA, and 2017 ASH President, gives his top picks of the most exciting areas of hemonc to look out for over the coming year.