With the increasing complexity of clinical trials, the role of the Clinical Research Nurse (CRN) and the Clinical Nurse Specialist (CNS) continues to evolve. In this interview, recorded at the 2017 National Cancer Research Institute (NCRI) Conference, held in Liverpool, UK, Anne Croudass, Lead Research Nurse at Cancer Research UK, London, UK, discusses the shift from the CRN and CNS focusing solely on specific roles, to focusing on the importance of the patients needs and how their experience can be improved.