Francine Foss, MD, from the Yale University School of Medicine, New Haven, CT, discusses targeting chemokines at the International Workshop on Non-Hodgkin Lymphoma (iwNHL) 2017 meeting, held in Vancouver, BC, Canada. Chemokines are a group of molecules that are expressed in the microenvironment of T- and B-cell malignancies. The anti-CCR4 antibody has been developed, and there is now research into whether there is a role for other chemokine therapy in lymphoma. There is also the possibility for targeting specific chemokines that affect the growth of the tumor cell to be targeted, as well as those associated with migration and metastasis.
Targeting chemokines in lymphoma
