An exciting array of data for myeloproliferative neoplasms (MPNs) was presented at the 2018 British Society for Hematology (BSH) Annual Scientific Meeting, held in Liverpool, UK. Speaking from the meeting, Claire Harrison, MD, FRCP, FRCPath, from Guys and St Thomas Hospital NHS Foundation Trust, London, UK, talks about the exciting clinical trials currently being conducted in MPNs. Prof. Harrison discusses a study aiming to improve the management of very young MPN patients, which may be used as a pilot to set up a collaboration across Europe, to rapidly generate data that can be used in further understanding this patient population and complication risks. She also mentions several promising new drugs in MPNs, including interesting combinations, such as those with BET inhibitors.