In recent years, the interest of the scientific community in the immune system as it relates to cancer has greatly increased, with the advent of immunotherapies being used as cancer treatments. In this interview, recorded at the 2017 National Cancer Research Institute (NCRI) Conference, held in Liverpool, UK, Jerome Galon, PhD, of Cordeliers Research Center, Paris, France, gives an introduction to his talk at the conference, the immunoscore, an evaluation of the immune response to cancer and the tumor microenvironment.