PALOMA-1 study of palbociclib in ER+, HER2-, breast cancer | Dr Véronique Diéras at St. Gallen Breast Cancer Conference 2015

At the 14th St. Gallen International Breast Cancer Conference 2015, Dr Véronique Diéras (Institut Curie, Paris, France) discusses the phase 2 PALOMA-1 study of the cyclin-dependent kinase 4/6 inhibitor, palbociclib, in combination with letrozole versus letrozole alone as first-line treatment for women with oestrogen receptor-positive (ER+), HER2-negative (HER2-), advanced breast cancer. The addition of palbociclib to letrozole significantly improved progression-free survival in this patient population. A phase 3 trial is in progress.

European Medical Journal

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