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Home » Page 33

Osimertinib Frontline for EGFR Mutated Resistance Mechanisms Not Fully Understood

Acute Lymphoblastic Leukemia 2 Mins Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses Osimertinib in front-line for EGFR mutated resistance mechanisms and how…

Serious Illness Conversation Guides Helpful in Creating Mutual Goals

Acute Lymphoblastic Leukemia 2 Mins Read

Beth Eaby-Sandy, MSN, CRNP of University of Pennsylvania talks about the serious illness conversation guides and how they can be…

Turning Cold Tumors into Hot Tumors Using Immune Therapy Resistance

Acute Lymphoblastic Leukemia 1 Min Read

Vassiliki Papadimitrakopoulou, MD of MD Anderson Cancer Center discusses turning cold tumors into hot tumors using agents that address immune…

Mesothelioma Trends in 2018 PrECOG and Ipi Nivo v Chemo

Acute Lymphoblastic Leukemia 1 Min Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses mesothelioma trends in 2018 with PrECOG and Ipi Nivo v…

Small Cell Lung Cancer New Approaches Using Immunotherapy

Acute Lymphoblastic Leukemia 2 Mins Read

Charles Rudin, MD, PhD of Memorial Sloan Kettering Cancer Center discusses small-cell lung cancer new approaches using immunotherapy. Small-cell lung…

Patient Conversations with Loved One Engage With Patient First and Foremost

Acute Lymphoblastic Leukemia 2 Mins Read

Beth Eaby-Sandy, MSN, CRNP of University of Pennsylvania explains that in patient conversations with loved ones, it’s the best to…

NSCLC Checkpoint Combinations Epacadostat, IL-2 & IL-10

Acute Lymphoblastic Leukemia 1 Min Read

Vassiliki Papadimitrakopoulou, MD of MD Anderson Cancer Center discusses NSCLC checkpoint inhibitors with the combinations of Epacadostat and IL-2 and…

Mesothelioma New Salvage Guidelines Pembrolizumab & Ipilimumab Nivolumab

Acute Lymphoblastic Leukemia 1 Min Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses the new salvage guidelines for mesothelioma, including pembrolizumab & ipilimumab…

Rovalpituzumab Tesirine (Rova-T) A DLL3 Target in SCLC

Acute Lymphoblastic Leukemia 1 Min Read

Charles Rudin, MD, PhD of Memorial Sloan Kettering Cancer Center discusses Rovalpituzumab Tesirine (Rova-T) a DLL3 target in SCLC. According…

Checkpoint Inhibitors as First Line Pembrolizumab Alone and in Combination

Acute Lymphoblastic Leukemia 1 Min Read

Vassiliki Papadimitrakopoulou, MD of MD Anderson Cancer Center discusses checkpoint inhibitors as first line therapy, pembrolizumab alone and in combination…

Patient Conversation Management I hope but I worry

Acute Lymphoblastic Leukemia 1 Min Read

Beth Eaby-Sandy, MSN, CRNP of University of Pennsylvania discusses patient conversation management and the “I hope but I worry” phrase.…

LUME-Meso Trial Pemetrexed, Cisplatin and Nintedanib Superior PFS

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Anne S. Tsao, MD of MD Anderson Cancer Center discusses about their study of LUME-MESO Trial for mesothelioma treatment.…

Osimertinib Real World Toxicity Substantially Less than 1st Gen TKIs

Acute Lymphoblastic Leukemia 1 Min Read

Charles Rudin, MD, PhD of Memorial Sloan Kettering Cancer Center discusses Osimertinib, its real world toxicity issues and comparison with…

Barriers to Patient Communication Advertising, Clinical Jargon, Hopeful Messaging

Acute Lymphoblastic Leukemia 2 Mins Read

Beth Eaby-Sandy, MSN, CRNP of University of Pennsylvania discusses barriers to patient communication advertising, clinical jargon, and encouraging hopeful messages,…

2018 Significant NSCLC Trials EMPOWER, KEYNOTE-189, & MYSTIC

Acute Lymphoblastic Leukemia 1 Min Read

Vassiliki Papadimitrakopoulou, MD of MD Anderson Cancer Center discusses the 2018 significant NSCLC trials including EMPOWER, KEYNOTE-189, & MYSTIC. This…

IFCT MAPS trial PFS and Overall Benefit in Front Line Mesothelioma

Acute Lymphoblastic Leukemia 1 Min Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses IFCT MAPS trial, the PFS and overall benefit in front-line…

Osimertinib in First Line What About Second Line Treatment

Acute Lymphoblastic Leukemia 1 Min Read

Charles Rudin, MD, PhD of Memorial Sloan Kettering Cancer Center talks about using Osimertinib in first line and possible shift…

PV Reporter interviews Dr. Raajit Rampal at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Advanced Forms of MPNs are Associated with Chromosomal Abnormalities Involved in Disease Progression

Thoracic Oncology in 2018 Finding Better Biomarkers

Acute Lymphoblastic Leukemia 1 Min Read

Joshua Bauml, MD of the University of Pennsylvania discusses thoracic oncology in 2018 and the importance of finding better biomarkers.…

Pre-Operative Questions for NSCLC

Acute Lymphoblastic Leukemia 1 Min Read

Jessica S. Donington, MD of NYU Langone Health discusses pre-operative questions for NSCLC patient treatment. Determining resectable patients from a…

Osimertinib Versus Erlotinib or Gefitinib in The FLAURA Trial

Acute Lymphoblastic Leukemia 1 Min Read

Joshua Bauml, MD of the University of Pennsylvania discusses Osimertinib versus Erlotinib or Gefitinib in the FLAURA Trial. Osimertinib did…

IASLC Lung Cancer Staging Project Why Aren Some Factors Not Included

Acute Lymphoblastic Leukemia 1 Min Read

Jessica S. Donington, MD of NYU Langone Health talks about the IASLC Lung Cancer Staging Project and why some factors…

Next Generation Sequencing Assays Will Allow More Targeting in Specific Patients

Acute Lymphoblastic Leukemia 1 Min Read

Joshua Bauml, MD of the University of Pennsylvania discusses the next generation sequencing assays that will allow more targeting in…

IASLC Lung Cancer Staging Project Understanding the Complexities

Acute Lymphoblastic Leukemia 1 Min Read

Jessica S. Donington, MD of NYU Langone Health discusses IASLC lung cancer staging project, important changes and complexities. There are…

MET Exon 14 Skipping Mutations and Crizotinib

Acute Lymphoblastic Leukemia 1 Min Read

Joshua Bauml, MD of the University of Pennsylvania discusses MET Exon 14 Skipping Mutations and Crizotinib. This is an important…

Changes in Stage 3A NSCLC Using Immunotherapy In Resectable Patients

Acute Lymphoblastic Leukemia 1 Min Read

Jessica S. Donington, MD of NYU Langone Health discusses the changes in stage 3A NSCLC using immunotherapy in resectable patients.…

Immunotherapy in Lung Cancer Unselected Patients Response Rate 15-20 Percent

Acute Lymphoblastic Leukemia 1 Min Read

Joshua Bauml, MD of the University of Pennsylvania discusses immunotherapy in lung cancer and the 15-20 percent response rate of…

Surgical Dilemmas in the Management of Locally Advanced NSCLC

Acute Lymphoblastic Leukemia 2 Mins Read

Jessica S. Donington, MD of NYU Langone Health discusses the surgical dilemmas in the management of locally advanced NSCLC. Dr.…

HER2 Over Expressed in 60 percent of NSCLC

Acute Lymphoblastic Leukemia 1 Min Read

Joshua Bauml, MD of the University of Pennsylvania discusses the fact that HER2 is over expressed in 60 percent of…

T790M Testing Practically Standard for EGFR Activating Patients

Acute Lymphoblastic Leukemia 1 Min Read

Corey J. Langer, MD, FACP of the University of Pennsylvania discusses how T790M testing is practically standard for EGFR activating…

Pacific Trial Durvalumab in Locally Advanced NSCLC Strikingly Positive Data

Acute Lymphoblastic Leukemia 1 Min Read

Corey J. Langer, MD, FACP of the University of Pennsylvania discusses the Pacific Trial overview of Durvalumab in locally advanced…

The Three Levels of Smoking Cessation

Acute Lymphoblastic Leukemia 1 Min Read

Laura Jean Bierut, MD of Washington University of Medicine discusses the three levels of smoking cessation. These levels are (1)…

PACIFIC Trial Concerns Survival Data Not Released – PFS May Not Be Enough

Acute Lymphoblastic Leukemia 2 Mins Read

Corey J. Langer, MD, FACP of the University of Pennsylvania discusses his concerns over the PACIFIC Trial data such as…

E-Cigarettes Better Than Combustible Cigarettes

Acute Lymphoblastic Leukemia 1 Min Read

Laura Jean Bierut, MD of Washington University of Medicine discusses the benefits of E-Cigarettes over combustible cigarettes. First and foremost,…

FLAURA Trial Results 8-9 Month PFS in Treatment Naive EGFR

Acute Lymphoblastic Leukemia 1 Min Read

Corey J. Langer, MD, FACP of the University of Pennsylvania talks about the FLAURA Trial Results and the 8-9 Month…

E-Cigarettes May Be The Greatest Public Health Benefit This Century

Acute Lymphoblastic Leukemia 1 Min Read

Laura Jean Bierut, MD of Washington University of Medicine talks about E-Cigarettes and how they may be the greatest public…

In EGFR Activating Mutations Osimertinib is Now The Standard of Care

Acute Lymphoblastic Leukemia 1 Min Read

Corey J. Langer, MD, FACP of the University of Pennsylvania discusses how in EGFR Activating Mutations, Osimertinib is now the…

Two Main Nicotine Responders Genetic Variations and Metabolic Enzymes

Acute Lymphoblastic Leukemia 1 Min Read

Laura Jean Bierut, MD of Washington University of Medicine discusses the two main nicotine responders genetic variations and metabolic enzymes.…

2018 NSCLC Trends in Prognosticate Refinement and the "Tsunami" of Trials Assessing Combinations of Drugs

Acute Lymphoblastic Leukemia 2 Mins Read

Corey J. Langer, MD, FACP of the University of Pennsylvania talks about 2018 NSCLC trends in prognosticate refinement and the…

440,000 vs 60,000 fatalities per year Lung Cancer vs Opioid Crisis

Acute Lymphoblastic Leukemia 1 Min Read

Laura Jean Bierut, MD of Washington University of Medicine discusses 400,000 vs 60,000 fatalities per year lung cancer vs opioid…

What Determines using Osimertinib in First Line Treatment

Acute Lymphoblastic Leukemia 1 Min Read

Tracey L. Evans, MD of the University of Pennsylvania describes what determines using osimertinib in first line treatment. Dr. Evans…

Osimertinib & Small Cell Transformation

Acute Lymphoblastic Leukemia 1 Min Read

Lyudmila Bazhenova, MD of the University of California, San Diego discusses osimertinib & small cell transformation. There is a very…

T790 Mutation Testing on Initial Diagnosis

Acute Lymphoblastic Leukemia 1 Min Read

Tracey L. Evans, MD of the University of Pennsylvania discusses T790 mutation testing on initial diagnosis. Testing T790M before the…

Managing EGFR-Resistant Disease T790 and Beyond

Acute Lymphoblastic Leukemia 1 Min Read

Lyudmila Bazhenova, MD of the University of California, San Diego discusses management of EGFR-resistant disease and T790M mutations. Management of…

When To Focus on Smoking Cessation

Acute Lymphoblastic Leukemia 1 Min Read

Laura Jean Bierut, MD of Washington University of Medicine talks about when to focus on smoking cessation. There are two…

Incomplete Resections in NSCLC

Acute Lymphoblastic Leukemia 1 Min Read

Tracey L. Evans, MD of the University of Pennsylvania discusses incomplete resections in NSCLC. What to do with incomplete resection,…

FLAURA Study Improvement PGFS Over Standard Chemo

Acute Lymphoblastic Leukemia 1 Min Read

Lyudmila Bazhenova, MD of the University of California, San Diego discusses the FLAURA study and improvement in PFS over standard…

Impact of Immunotherapy in Thoracic Oncology

Acute Lymphoblastic Leukemia 1 Min Read

Tracey L. Evans, MD of the University of Pennsylvania discusses the impact of immunotherapy in thoracic oncology. Immunotherapy data is…

Is Osimertinib Ready for First Line?

Acute Lymphoblastic Leukemia 1 Min Read

Lyudmila Bazhenova, MD of the University of California, San Diego discusses T790M mutation and the role of osimertinib in the…

Why is Breakthrough of Osimertinib in EGFR Mutated NSCLC Important

Acute Lymphoblastic Leukemia 1 Min Read

Tracey L. Evans, MD of the University of Pennsylvania describes why Osimertinib is such an important breakthrough in EGFR mutated…

Metastatic EGFR Mutation + NSCLC First Line, Second Line, Third Line

Acute Lymphoblastic Leukemia 2 Mins Read

Lyudmila Bazhenova, MD of the University of California, San Diego discusses Metastatic EGFR mutation + Osimertinib in NSCLC first line,…

T Effector Gene Signature on IMpower150: Is There a Better Biomarker than PD-L1 for Immunotherapy? (BMIC-021)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West reviews provocative biomarker results on the IMpower150 trial that tested atezolizumab with carboplatin/paclitaxel +/- bevacizumab & revealed…

PV Reporter interviews Dr. Michael Grunwald at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Patient reported symptom burden and peripheral blood counts among PV patients.

The role of the nurse in elderly cancer patient care

Acute Lymphoblastic Leukemia 1 Min Read

Elderly cancer patients tend to have more complex conditions, and therefore require a strong support system to assist their needs…

Person-centered care and the elderly cancer patient: an important issue

Acute Lymphoblastic Leukemia 1 Min Read

With age being the biggest risk factor for cancer, and an ageing population in the UK, the NHS is having…

ASH 2017 top picks: Phase III trials, antibody-drug conjugates and CAR T-cells

Acute Lymphoblastic Leukemia 1 Min Read

The American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, presented cutting-edge updates in hematology. Discover…

MPNs update from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

In this exciting interview, Claire Harrison, MD, DM, FRCP, FRCPath, of Guy’s and St Thomas’ NHS Foundation Trust, London, UK,…

PT-1 study update: addition of hydroxyurea to aspirin in essential thrombocythemia

Acute Lymphoblastic Leukemia 1 Min Read

The primary thrombocythemia (PT)-1 trial (NCT00175838) comprises a series of three studies, which have been running since 1997 and include…

AML highlights from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

There was a long period of time without new acute myeloid leukemia (AML) treatments, but now there are a number…

Exciting new developments in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

This is an incredibly exciting time for multiple myeloma (MM) research. In this video, some of the most interesting topics…

Atezolizumab in First Line NSCLC: Early Clinical Results from the IMpower150 Trial (BMIC-020)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West reviews the preliminary clinical results on the IMpower150 trial that tested the value of adding the immune…

IMPACT: a UK clinical trials programme for hemonc patients post-transplant

Acute Lymphoblastic Leukemia 1 Min Read

The University of Birmingham has partnered with Leuka, NHS Blood and Transplant, and Anthony Nolan to deliver the UKs first…

From the bench to bedside: AML treatment

Acute Lymphoblastic Leukemia 1 Min Read

Understanding the biology of human disease is of the utmost importance to advancing treatment. We are now making excellent headway…

Oral azacitidine maintenance therapy for post-transplant AML

Acute Lymphoblastic Leukemia 1 Min Read

Relapse remains the main obstacle for patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) after allogeneic stem cell…

Azacitadine/HDAC inhibitor combination for high risk AML: a promising pilot study

Acute Lymphoblastic Leukemia 1 Min Read

For high-risk acute myeloid leukemia (AML), azacitidine monotherapy is typically utilized. However, there is a low overall response rate and…

New salvage treatment for AML/MDS after allogeneic transplant: the VIOLA trial

Acute Lymphoblastic Leukemia 1 Min Read

The outcome for patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) after allogeneic stem cell transplantation remains poor.…

Early Use of Chemotherapy for Prostate Cancer?

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Susanne Osanto discusses the use of chemotherapy plus androgen deprivation therapy (ADT) for newly diagnosed men with advanced stage…

MMRF updates from ASH 2017: CoMMpass study, transplant outcomes and the molecular profiling protocol

Acute Lymphoblastic Leukemia 1 Min Read

The Multiple Myeloma Research Foundation (MMRF) has been very active throughout 2017. Here, Daniel Auclair, PhD, of the MMRF, Norwalk,…

Lessons from the ASPIRE trial: three drug regimens as the new SOC for relapsed MM

Acute Lymphoblastic Leukemia 1 Min Read

Clinical trials and research, regardless of their degree of success, provide useful lessons that can be applied to a range…

ASPIRE trial for MM: updates from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

The ongoing Phase III ASPIRE trial (NCT01080391) comparing carfilzomib, lenalidomide and dexamethasone (CRd) vs. lenalidomide and dexamethasone (Rd) in patients…

Venetoclax combination studies showing great promise at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Venetoclax is a BCL-2 inhibitor used in the treatment of chronic lymphocytic lymphoma (CLL), which works through increasing the apoptosis…

Novel PD-1 inhibitor and BTK inhibitor combination: tislelizumab and zanubrutinib

Acute Lymphoblastic Leukemia 1 Min Read

Phase I studies investigating a new monoclonal antibody that works through the inhibition of PD-1 have shown similar levels of…

Advancements at ASH 2017 that are directly relevant to patients: genomic characterization and immunology

Acute Lymphoblastic Leukemia 1 Min Read

There were many advancements presented at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA,…

The future is bright for hematological oncology: promising areas for 2018 and beyond

Acute Lymphoblastic Leukemia 1 Min Read

The scientific advances reported at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, were…

ASH: setting the scene for new standards of care

Acute Lymphoblastic Leukemia 1 Min Read

The American Society of Hematology (ASH) Annual Meeting and Exposition has become the go-to place for hematology updates for scientists,…

ASH 2017 President’s meeting highlights

Acute Lymphoblastic Leukemia 1 Min Read

This years American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, presented major advances in hematology,…

Key abstracts being presented at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

The American Society of Hematology (ASH) 2017 Annual Meeting and Exposition, held in Atlanta, GA, showcased the most cutting-edge data…

Latest research in Hodgkin lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

Athough new molecules have advanced the treatment of Hodgkin lymphoma considerably in recent years, research is still ongoing to achieve…

Progress still being made in MM: highlights of ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Although the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition, held in Atlanta, GA, may not have had…

Using next generation flow to measure MRD in multiple myeloma patients

Acute Lymphoblastic Leukemia 1 Min Read

The monitoring of minimal residual disease (MRD) is important in predicting relapse and giving a more sensitive measurement to clinicians…

Venetoclax resistance and alternative treatments in CLL

Acute Lymphoblastic Leukemia 1 Min Read

Although little is currently known about the mechanisms of resistance to venetoclax, researchers are constantly looking for new drugs that…

Novel venetoclax combination therapy advancing the field of CLL

Acute Lymphoblastic Leukemia 1 Min Read

In chronic lymphocytic leukemia (CLL), venetoclax has established itself as one of the most effective monotherapies in certain contexts. Speaking…

Financial benefit of combining two expensive drugs for CLL

Acute Lymphoblastic Leukemia 1 Min Read

Venetoclax and ibrutinib are two relatively new drugs being used for the treatment of chronic lymphocytic leukemia (CLL), and although…

Social media as a professional tool for hematologists

Acute Lymphoblastic Leukemia 1 Min Read

Social media platforms, such as Twitter, are a staple of the modern world and facilitate communication between people from all…

CAR T-cell therapy in Europe: transporting cells to the USA

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cell therapy has emerged as a highly promising cancer treatment in recent years, with patient’s own cells being modified…

The Geriatric Assessment in Hematology (GAH) scale

Acute Lymphoblastic Leukemia 1 Min Read

As age increases, the likelihood of a patients with hematological malignancies having further complications and comorbidities increases. Speaking from the…

Immunotherapy discussions at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy has been a primary area of focus in lymphoma research in recent years, with treatments looking to stimulate and…

Key Insights: Lymphoma & Myeloma 2017 – CLL

Acute Lymphoblastic Leukemia 1 Min Read

In this activity, Congress Chair Dr. Morton Coleman and CLL Session Co-Chair Dr. Richard R. Furman discuss highlights of the…

Key Insights: Lymphoma & Myeloma 2017 – Lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

In this Key Insights activity, Congress Chair Dr. Morton Coleman and Lymphoma Session Co-Chair Dr. John Leonard discuss highlights of…

Primary analysis of MURANO study data for R/R CLL

Acute Lymphoblastic Leukemia 1 Min Read

Updates from the highly anticipated Phase III MURANO study (NCT02005471) in relapsed/refractory chronic lymphocytic leukemia (CLL) were presented at the…

Key Insights: Lymphoma & Myeloma 2017 – Multiple Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

In this Key Insights activity, Drs. Morton Coleman and Ruben Niesvizky discuss highlights of the first day of Lymphoma &…

New nivolumab combination therapies for AML

Acute Lymphoblastic Leukemia 1 Min Read

There has historically been less novel agents being tested and moving into the clinic for AML. Now, there has been…

Exciting novel AML treatment: venetoclax plus cobimetinib or idasanutlin in elderly patients

Acute Lymphoblastic Leukemia 1 Min Read

Venetoclax combinations have shown excellent results in chronic lymphocytic leukemia (CLL), but are now, excitingly, displaying fantastic preliminary outcomes in…

Investing in nurse development: facilitating communication within and across CNS teams

Acute Lymphoblastic Leukemia 1 Min Read

Although a key skill of nursing is communication with patients and the multidisciplinary team, ensuring good communication channels within and…

UKONS 2017: speaking under time pressure

Acute Lymphoblastic Leukemia 1 Min Read

Nursing is a demanding job, with the many responsibilities and patients meaning that nurses are often under considerable time pressure.…

Acute oncology: new immunotherapy guidelines

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapies can come with a range of toxicities that require the appropriate management by acute oncology services. In this interview,…

Center experience: immunotherapy in Southampton

Acute Lymphoblastic Leukemia 1 Min Read

As novel immunotherapies are introduced into practice, centers need to implement new protocols and educate staff in order to ensure…

The rarer toxicities of immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapies can induce a range of common, as well as rare, side effects. These may be difficult for healthcare professionals…

The systemic anti-cancer dataset (SACT): optimizing immunotherapy toxicity management

Acute Lymphoblastic Leukemia 1 Min Read

Collating data and communicating center experiences is essential to ensure that the best standard of care is provided to patients…

Early Use of Chemotherapy for Prostate Cancer?

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Susanne Osanto discusses the use of chemotherapy plus androgen deprivation therapy (ADT) for newly diagnosed men with advanced stage…

Practical intricacies surrounding biosimilar adoption

Acute Lymphoblastic Leukemia 1 Min Read

There are many intricacies surrounding the introduction of biosimilars. Here, Simon Cheesman, BPharm, MRPharmS from University College London Hospital (UCLH),…

The introduction of biosimilar rituximab: a case study from the pharmacist’s perspective

Acute Lymphoblastic Leukemia 1 Min Read

“During the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium for cancer care pharmacy in Glasgow, UK, Simon Cheesman, BPharm,…

The role of pharmacists for driving the integration of biosimilar monoclonal antibodies into practice

Acute Lymphoblastic Leukemia 1 Min Read

“During the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium for cancer care pharmacy in Glasgow, UK, Simon Cheesman, BPharm,…

The challenges of cancer research and the critical role of the pharmacist

Acute Lymphoblastic Leukemia 1 Min Read

“Peter Johnson, BA, MB BChir, MA, MRCP, MD, FRCP from Southampton General Hospital, Southampton, UK, summarises the challenges of cancer…

Advancing cellular therapies for blood cancers

Acute Lymphoblastic Leukemia 1 Min Read

David Irvine from the Beatson Institute, Glasgow, UK outlines his presentation on cellular advances in hematological oncology given at the…

The benefits of having academics who work clinically

Acute Lymphoblastic Leukemia 1 Min Read

Having academics who also work in the clinic has a wide range of benefits. In this interview, Naomi Farrington, PhD,…

The services improving elderly cancer patient care

Acute Lymphoblastic Leukemia 1 Min Read

Elderly cancer patients are likely to have comorbidities and more complex treatment needs, which can result in certain treatments not…

Challenges facing elderly cancer patients

Acute Lymphoblastic Leukemia 1 Min Read

Elderly patients comprise the majority of cancer cases; however, they are often overlooked in many facets of oncology research and…

Increasing role of the pharmacist in patient care

Acute Lymphoblastic Leukemia 1 Min Read

Pharmacists have an excellent knowledge of drugs and are an essential part of the multidisciplinary healthcare team. Excitingly, they are…

Patient education and the role of the nurse

Acute Lymphoblastic Leukemia 1 Min Read

Nurses have a high level of contact with individual patients, which enables them to have a unique perspective on their…

Managing the care of patients receiving oral systemic anti-cancer therapy (SACT)

Acute Lymphoblastic Leukemia 1 Min Read

The official recommendations are that patients taking oral systemic anti-cancer therapy (SACT) receive the same level as care as those…

The importance of research in cancer nursing

Acute Lymphoblastic Leukemia 1 Min Read

The debate at the UK Oncology Nursing Society (UKONS) Annual Conference 2017 in Harrogate, UK, focused on highlighting the importance…

Genomic Sequencing for All Solid Tumors: Where Will This Lead Us? (BMIC-019)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West reviews the implications, both encouraging and potentially detrimental, of a recent FDA approval for broad genomic (NGS)…

Myeloma 2017 day 2 highlights: MRD, targeted therapies and imaging advances

Acute Lymphoblastic Leukemia 1 Min Read

This is a very exciting time for multiple myeloma (MM) research, with advances in a range of areas from new…

Why use model systems for multiple myeloma research?

Acute Lymphoblastic Leukemia 1 Min Read

Model systems, including patient specimens and murine organisms, are very important for multiple myeloma (MM) research. Speaking from the Myeloma…

The future of immunotherapy in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

There is a plethora of therapies available for multiple myeloma (MM). In this insightful panel discussion at the Myeloma 2017…

Novel therapeutics in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

There are currently many exciting novel therapeutics and combination therapies undergoing clinical trials for use in multiple myeloma (MM) patients.…

An E-learning tool for hematology-oncology nurses

Acute Lymphoblastic Leukemia 1 Min Read

A key finding of a recent Bloodwise study into the specific needs of hematological cancer patients highlighted the importance of…

Curbing cancer patientsÂ’ expectations of immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy is a growing treatment area for cancer, with a lot of hype in the mainstream media. In this interview,…

The adapting role of the cancer nurse: immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy has received a lot of coverage as a revolutionary cancer treatment, in both the medical community and in the…

Nurses and the growth of personalized cancer care

Acute Lymphoblastic Leukemia 1 Min Read

In recent years, molecular tests have emerged that can help provide information about cancers, such as determining what type of…

New Target & Treatment in Advanced NSCLC: Dabrafenib/Trametinib for BRAF V600E Mutation-Positive NSCLC (BMIC-018)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West reviews data on the FDA-approved combination of dabrafenib/trametinib for patients with BRAF V600E mutation-positive advanced NSCLC, as…

Reducing late symptom reporting: a holistic approach in cancer nursing

Acute Lymphoblastic Leukemia 1 Min Read

It is critical that cancer patients report the side effects of their treatments, whether chemotherapy or immunotherapy, as early as…

Person-centered care and the elderly cancer patient: an important issue

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With age being the biggest risk factor for cancer, and an ageing population in the UK, the NHS is having…

The future tailoring of MM treatment

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Recent studies presented at the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium 2017 in Glasgow, UK have identified multiple…

Unprecedented clinical trial results for MM

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The data from several recent monoclonal antibody clinical trials for multiple myeloma (MM), which are producing very exciting results, was…

TOURMALINE-MM1 study produces optimistic results for MM

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The ongoing TOURMALINE-MM1 study (NCT01564537), a Phase III placebo-controlled clinical trial for relapsed refractory multiple myeloma, has produced very positive…

ASPIRE update: promising results for MM

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There have been promising preliminary results from the ongoing ASPIRE study (NCT01080391), a Phase III clinical trial for patients with…

New additions: novel agents to boost treatment of mulitple myeloma

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Alberto Rocci, MD from the Central Manchester University Hospital, Manchester, UK discusses the encouraging data from recent clinical trials, looking…

Re-evaluating the role of epigenetics in multiple myeloma

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Exciting advances in our knowledge of the epigenetics of multiple myeloma (MM) have recently been made. Speaking at the Myeloma…

Debate on the use of MRD for multiple myeloma management

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The highly anticipated panel discussion on the hot topic of MRD at the Myeloma 2017 meeting in Edinburgh, UK produced…

Myeloma 2017 day 1 highlights: immunotherapy advances, a new MM subtype and liquid biopsies

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Fantastic advances in immunotherapy, including CAR T-cells, bispecific antibodies and potential immunotherapy combinations, were presented at the Myeloma 2017 meeting…

Improving existing imaging technology for multiple myeloma

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The current baseline imaging technology for multiple myeloma (MM) management includes PET and MRI. In this interview, Ravi Vij, MD,…

The future of AML and MDS diagnosis and treatment

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There is currently a conundrum regarding the differentiation of acute myeloid leukemia and myelodysplastic syndromes. In this interview, Stéphane de…

The use of CAR T-cells in multiple myeloma

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The utilization of CAR T-cells for the treatment of multiple myeloma (MM) has great potential, with numerous different targets and…

The exciting field of imaging in multiple myeloma

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Research into imaging for multiple myeloma (MM) is expanding into an exciting new field, which is explored in this discussion…

Multiple myeloma: genomic evolution

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The mechanisms of therapy resistance in multiple myeloma (MM) are evolving. This is deliberated in this insightful discussion between Marc…

Exportin (XPO1) inhibitors for the treatment of AML

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Inhibitors of exportin (XPO1), a nuclear export chaperone, are currently in early clinical trials for acute myeloid leukemia (AML). Speaking…

Targeting non-coding RNAs in leukemia

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There are currently several novel agents that target non-coding RNAs being tested in pre-clinical studies for the treatment of leukemia.…

Novel targets for AML

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“There are currently a number of ongoing clinical trials for acute myeloid leukemia (AML) that are targeting nuclear exporters. In…

The spliceosome mutations that can cause hematological malignancies

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There are four commonly mutated spliceosome proteins in hematological malignancies. In this interesting interview, recorded at the International Conference on…

Efficacy of first generation FLT3 inhibitors for AML

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New molecules targeting specific gene mutations are showing great potential for precisely treating diseases and lowering the toxicity of treatment.…

Role of genetics in hematological malignancies: expanding our understanding

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Having an understanding of the inherited genetic components that can lead to cancer formation can be of great use to…

Holistic therapies as a supplement to pharmacological intervention in MPN

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Holistic therapies are often viewed unfavorably by the medical community, with many clinicians preferring to solely focus on pharmacological treatments.…

Looking forward: MPN treatment

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Myeloproliferative neoplasms (MPNs) are complex diseases, with current therapies primarily designed to prevent complications and reduce symptoms. In this insightful…

Liquid biopsies for multiple myeloma: the attractions and limits

Acute Lymphoblastic Leukemia 1 Min Read

“Technological advances have allowed for whole genome, exome and transcriptome sequencing of circulating multiple myeloma (MM) cells and cell-free tumor…

Liquid biospy approaches for detecting MM and their optimization

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It has become apparent in recent years that low levels of ciculating tumor DNA can be detected in multiple myeloma…

Detecting common mutations in MM patients through liquid biopsy

Acute Lymphoblastic Leukemia 1 Min Read

The detection of various gene mutations, such as those in Ras and Raf, are important for risk stratification and identifying…

Myeloma 2017: an epigenetic research boom

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The Myeloma 2017 meeting, held in Edinburgh, UK, saw more focus on epigenetic contributors to multiple myeloma (MM) than ever…

Where no man has gone before: the technologies being used to explore MM epigenetic factors

Acute Lymphoblastic Leukemia 1 Min Read

In recent years, researchers have become increasingly aware of the fact that epigenetic alterations can contribute to the formation of…

Exploring new worlds: the epigenetic contributors to multiple myeloma

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Although researchers are aware of the fact that epigenetic factors play a significant role in the development of multiple myeloma…

Fine-tuning our understanding of the immune system to utilize combination therapies for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

There are several different types of immunotherapy and associated conjunctional therapies currently being studied that have shown some degree of…

Dendritic cell vaccine for MM: progress so far

Acute Lymphoblastic Leukemia 1 Min Read

Cancer immunotherapy is a very active area of research at the moment, with the potential to treat a cancer long-term…

Drug resistance in multiple myeloma: addressing the issue

Acute Lymphoblastic Leukemia 1 Min Read

Drug resistance is a common problem in the treatment of multiple myeloma (MM), either through initial resistance to a drug,…

Molecular modelling of drug efficacy in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Clinical trials to determine the efficacy of a drug are costly, particularly when there are many subtypes of a certain…

Genetic elements driving IMiD resistance in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Immunomodulatory drugs (IMiDs) are a class of drugs including the likes of thalidomide, which are used in the treatment of…

Targeting DNA methylation as a therapeutic target in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Epigenetic modifications, such as DNA methylation, can lead to or complicate disease, and lead to worse patient outcomes. Speaking from…

Analyzing genetic and epigenetic markers of high-risk multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

The Multiple Myeloma Research Foundation (MMRF) is sponsoring the CoMMpass trial (NCT01454297), which aims to define subsets of multiple myeloma…

Working with smaller research companies

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Speaking from the International Conference on Acute Myeloid Leukaemia 2017, Estoril, Portugal by the European School of Haematology (ESH), Stéphane…

The next steps for the IDH2 inhibitor drug enasidenib

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The IDH2 inhibitor drug, enasidenib has previously only been administered to elderly populations with acute myeloid leukemia. Stéphane de Botton,…

The potential of differentiation therapies for AML

Acute Lymphoblastic Leukemia 1 Min Read

Stéphane de Botton, MD, PhD of the Gustave Roussy Institute, Villejuif, France, discusses the efficiency of differentiation therapies for the…

The rapid progression of IDH1/2 mutant enzyme inhibitors through clinical trials

Acute Lymphoblastic Leukemia 1 Min Read

In this video, Stéphane de Botton, MD, PhD of the Gustave Roussy Institute, Villejuif, France, describes the rapid progression of…

Price vs. performance: CAR T-cells

Acute Lymphoblastic Leukemia 1 Min Read

The potential advantage of a therapy compared to its cost is an important factor to consider when approving novel treatments.…

The need for collaboration amongst hospitals: learning from RATIFY

Acute Lymphoblastic Leukemia 1 Min Read

The recent RATIFY study (NCT00651261), which led to the approval of midostaurin for the treatment of FLT3-mutated AML patients, was…

Why are new molecules typically combined with standard chemotherapy?

Acute Lymphoblastic Leukemia 1 Min Read

When new drugs are being tested as a treatment for a cancer, they are typically trialled in combination with standard…

Integrating midostaurin into FLT3 positive AML treatment

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In the RATIFY clinical trial (NCT00651261), the FLT3 inhibitor midostaurin plus standard chemotherapy was shown to have an advantage over…

Combinations with FLT3 inhibitors: the way forward for AML treatment

Acute Lymphoblastic Leukemia 1 Min Read

The RATIFY trial (NCT00651261) showed that midostaurin, a FLT3 inhibitor that was a previously ineffective monotherapy for acute myeloid leukemia…

Resistance mechanisms to FLT3 inhibitors in AML

Acute Lymphoblastic Leukemia 1 Min Read

Over recent years, inhibition of excessive FLT3 signalling has been a primary area of research to find an effective targeted…

Infrastructure for AML treatment in Spain

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Acute myeloid leukemia (AML) is a complex disease with many subtypes; treatment can be more effective and efficient if there…

Finding novel treatment options for relapsed/progressing AML

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The long-term survival rate of acute myeloid leukemia (AML) patients who have relapsed, or whose disease is progressing, is poor.…

Transferring lessons learnt from treating ALL to AML

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Reflecting upon past research is key to the development of new treatments. In this interview at the International Conference of…

The development of novel treatment modalities: regulations and expectations

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Novel technologies have the potential to allow us to treat more ailments, but often come at the price of new…

CAR T-cells and CRISPR: The future of AML treatment

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New and invigorating methods of tackling acute myeloid leukemia (AML) are being researched at present. In this interview, Saar Gill,…

Game-changing treatments for leukemia

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This is an exciting time for leukemia treatment, with multiple new therapies being approved and various agents on the horizon.…

Pre-leukemic stem cells: a telltale sign of AML

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As innovative research investigating acute myeloid leukemia (AML) progresses, the chances of developing effective treatments against the ailment increase. In…

What may be causing heart and kidney issues in an elderly myeloma patient with no bone lesions%3F (1)

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Establishing standardized guidelines on eosinophilia investigation and management in the UK

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Eosinophilia is a highly variable disease that can be relatively mild or potentially fatal; it can occur due to primary…

Diagnosis, classification and treatment of systemic mastocytosis

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Systemic mastocytosis, though a rare disease, is more common than clinicians may think and diagnosis of the condition can often…

Potential of next-generation sequencing in the NHS for patients with MPNs

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Myeloproliferative Neoplasms (MPNs) carry a risk of complications, such as thrombosis; the degree of risk is influenced in part by…

The importance of collaboration in AML research

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It is well known that studying larger patient groups produces more robust results in research. Omar Abdel-Wahab, MD, from the…

Neomorphic mutations driving hematological cancers

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It is known that spliceosome gene mutations can drive hematological cancers, but there may also be neomorphic mutations at play.…

The Scottish Cancer Prevention Network: an exemplary advocacy group

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There is often a lack of communication about the strong evidence linking lifestyle to cancer risk. In this video, Annie…

Recruiting for cancer research lifestyle programs

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“Health service personnel are paramount in endorsing and conveying lifestyle messages that reduce the risk of cancer in the public.…

Changing societyÂ’s normative lifestyle behavior: the actions required to reduce cancer

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There is extensive and durable evidence supporting the link between lifestyle and cancer recurrence, yet this evidence is not being…

Designing effective lifestyle intervention trials

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“Lifestyle intervention trials rely heavily on cooperation from the patient group and thus, it is important to effectively engage these…

The importance of lifestyle intervention trials in cancer survivors

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“As a greater number of people are surviving cancer, this is an exciting time to determine the magnitude of effect…

Should Osimertinib Become First-Line Treatment of Choice for EGFR Mutation-Positive Advanced NSCLC, or Should it Be Saved for Later? (BMIC-017)

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Dr. Jack West reviews the pros and cons of using osimertinib first line vs. “saving” it as a second line…

Tackling CD47-positive malignancies

Acute Lymphoblastic Leukemia 1 Min Read

Innovative research has begun to create a novel therapy that could potentially treat a variety of malignancies, including acute myeloid…

An overview of immunotherapies for leukemia

Acute Lymphoblastic Leukemia 1 Min Read

As research into the different aspects of treating leukemia develops there will be an increase in the number of targeted…

Combination therapies and improving overall survival in AML

Acute Lymphoblastic Leukemia 1 Min Read

This is an exciting time for acute myeloid leukemia (AML), with the introduction of numerous novel combination therapies and the…

The therapeutics targeting splicing in hematological malignancies

Acute Lymphoblastic Leukemia 1 Min Read

Currently, the majority of therapeutics that target splicing mutations in hematological malignancies are in the early or pre-clinical phases. In…

What are the drivers of leukemia?

Acute Lymphoblastic Leukemia 1 Min Read

Mutations can change the function of a protein and thus be the driver of diseases. In this video, Omar Abdel-Wahab,…

The benefits of patient advocacy groups

Acute Lymphoblastic Leukemia 1 Min Read

Patient advocacy groups can be of great use to patients, giving them means to network with other patients and providing…

Developing an understanding of disease progression in MDS and AML

Acute Lymphoblastic Leukemia 1 Min Read

Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) increasingly appear to be influenced by genetic features, with new research attempting…

Balancing hereditary research with patient care in leukemia

Acute Lymphoblastic Leukemia 1 Min Read

In recent years, the medical community has become aware of certain genetic factors that can predispose someone to developing hematological…

The challenges of using kinase inhibitors for AML treatment

Acute Lymphoblastic Leukemia 1 Min Read

Using kinase inhibitors, such as midostaurin, to treat acute myeloid leukemia typically only produces a partial response. Mark Levis, MD,…

Venetoclax for elderly AML patients

Acute Lymphoblastic Leukemia 1 Min Read

The BCL2 inhibitor venetoclax has shown remarkable response rates in elderly acute myeloid leukemia (AML) patients when used in combination…

The drugs being used to treat newly diagnosed AML patients

Acute Lymphoblastic Leukemia 1 Min Read

“In this insightful interview, Mark Levis, MD, PhD, from The Johns Hopkins Hospital, Baltimore, MD, talks about the four primary…

One size does not fit all: AML subtype treatment approaches

Acute Lymphoblastic Leukemia 1 Min Read

Acute myeloid leukemia (AML) is no longer thought to be just a single disease; thus, each subtype needs to be…

AML immunotherapy: pre-clinical data to look forward to at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

It is still early days for immunotherapeutic strategies. Speaking from the International Conference on Acute Myeloid Leukemia 2017, Estoril, Portugal…

Is the order of mutations leading to cancer important?

Acute Lymphoblastic Leukemia 1 Min Read

Cancers, such as myeloproliferative neoplasms (MPNs), evolve from repeated mutations; it is unlikely that one mutation alone causes cancer. In…

The future of predicting outcomes for patients with MPNs: a patient knowledge bank

Acute Lymphoblastic Leukemia 1 Min Read

The discovery of various molecular risk factors for myeloproliferative neoplasms (MPNs) has revolutionized the way in which doctors diagnose these…

Communication and safety when treating patients undergoing immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Nurses provide a high level of contact to a patient with cancer, which is essential in order to educate them…

Adapting acute oncology services to immunotherapy

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An acute oncology service works to manage the unexpected care needs of patients with cancer. In this interview, recorded at…

Center experience: immunotherapy at the Royal Marsden

Acute Lymphoblastic Leukemia 1 Min Read

The use of immunotherapy in the UK as a treatment for cancer has increased over the past decade. In this…

Role of the immunotherapy clinical nurse specialist

Acute Lymphoblastic Leukemia 1 Min Read

Clinical Nurse Specialists (CNSs) play a key role for a cancer patient, in both performing clinical procedures, and offering psychological…

The value of UKONS

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Conferences can be a fantastic opportunity to network within a certain profession, and get an idea of the challenges that…

Developing leadership skills in nursing

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Nurses in the UK are highly valued as part of the multidisciplinary health team. However, as Daniel Kelly, PhD, from…

Recognizing cancer nursing: a study across Europe

Acute Lymphoblastic Leukemia 1 Min Read

Specialist cancer nurses play a vital role in improving patient care, in both clinical and psychological contexts. In this interview,…

Improving existing imaging technology for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

The current baseline imaging technology for multiple myeloma (MM) management includes PET and MRI. In this interview, Ravi Vij, MD,…

Imaging advances in multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Radiological advances are now enabling us to decipher the disease biology of multiple myeloma (MM) in ways that were previously…

Game-changing drug classes for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

There are two new highly promising classes of treatments for multiple myeloma. Speaking from the Myeloma 2017 meeting in Edinburgh,…

Why one size should not fit all for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Within multiple myeloma (MM), there are biologically different diseases that are distinctly characterized. In this video, Gareth Morgan, MD, FRCP,…

Identifying the drivers of multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

There has been a genome-wide initiative to identify the copy number variants and mutational drivers of multiple myeloma. In this…

Dacomitinib: Dark Horse EGFR TKI Charges into a Crowded First Line Setting for EGFR Mutation-Positive Advanced NSCLC (BMIC-016)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West reviews the results of the ARCHER-1050 trial that showed superior efficacy with dacomitinib vs. gefitinib in EGFR…

The biases of using bone marrow biopsies for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

A full understanding of the methods available for diagnosis, prognosis and stratification are required in order to choose the optimal…

AML immunotherapy: patients need to be well informed

Acute Lymphoblastic Leukemia 1 Min Read

Although there is a lot of hope and optimism surrounding immunotherapy, Marion Subklewe, MD, of the University of Munich, Munich,…

AML clinical trials: early stage vs. relapse/refractory patients

Acute Lymphoblastic Leukemia 1 Min Read

Cinical trials for acute myeloid leukemia (AML) typically only include relapsed/refractory patients, rather than patients at an earlier stages of…

T-cell engaging antibodies: what lessons have we learnt?

Acute Lymphoblastic Leukemia 1 Min Read

The use of T-cell engaging antibodies for acute myeloid leukemia (AML) treatment is in the very early stages. In this…

Selecting AML patients for intensive treatment

Acute Lymphoblastic Leukemia 1 Min Read

Many variables are involved in selecting the type of treatment that a patient can receive. Speaking from the International Conference…

Advising AML patients to participate in clinical trials

Acute Lymphoblastic Leukemia 1 Min Read

The widespread accessing of new drugs by HCPs and patients can be a very long process. Currently, venetoclax is in…

Upcoming clinical trials for venetoclax chemotherapy combinations for AML

Acute Lymphoblastic Leukemia 1 Min Read

“This is an exciting time for new acute myeloid leukemia (AML) therapies, particularly combination treatments. In this video, Marina Konopleva,…

Promising results for venetoclax combination therapies in elderly AML

Acute Lymphoblastic Leukemia 1 Min Read

“In this exciting interview, Marina Konopleva, MD, PhD of the MD Anderson Cancer Center, Houston, TX, provides optimistic preliminary results…

Reassuring patients with AML

Acute Lymphoblastic Leukemia 1 Min Read

Compassion and understanding are two key components within medical care. At the International Conference of Acute Myeloid Leukaemia 2017 in…

Translational research in Berlin to improve AML treatment outcomes

Acute Lymphoblastic Leukemia 1 Min Read

New research methods enable a greater understanding of a disease and allow for more personalized medicine to be produced. In…

Adapting AML treatment for elderly patients

Acute Lymphoblastic Leukemia 1 Min Read

The effective use of the correct medication can greatly improve the chance of remission for patients with acute myeloid leukemia…

Risks and treatments for pregnant MPN patients

Acute Lymphoblastic Leukemia 1 Min Read

Though women of childbearing age are diagnosed with myeloproliferative neoplasms (MPNs) less frequently than the general population, it is key…

The cause and effect of inflammation in MPNs

Acute Lymphoblastic Leukemia 1 Min Read

Chronic inflammation is a key hallmark of myeloproliferative neoplasms (MPNs) and is responsible for many of the symptoms that affect…

The challenges facing elderly AML treatment

Acute Lymphoblastic Leukemia 1 Min Read

To effectively treat acute myeloid leukemia (AML) in elderly patients, it is important that therapies for the right demographic are…

Identifying risk factors for thrombosis in MPNs and treatment strategies

Acute Lymphoblastic Leukemia 1 Min Read

Thrombosis is a major risk factor for early mortality in patients with myeloproliferative neoplasms (MPNs), particularly essential thrombocythemia and polycythemia…

Providing the relevant information to patients: a changing approach in Spain

Acute Lymphoblastic Leukemia 1 Min Read

As patient awareness and knowledge of disease increases, the way in which doctors provide information to their patients in Spain…

MPN Advances day 2017: latest updates in the field

Acute Lymphoblastic Leukemia 1 Min Read

Myeloproliferative neoplasms are complex diseases, with new research constantly updating our understanding of risk factors that may cause the diseases…

What are the alternative treatment options for relapsed or elderly AML patients?

Acute Lymphoblastic Leukemia 1 Min Read

For relapsed and elderly acute myeloid leukemia patients, standard treatment is often not good enough. In this interview, Jorge Sierra,…

Integrating molecular variables into prognostic models for patients with MPNs

Acute Lymphoblastic Leukemia 1 Min Read

In this interview, Alessandro Vannucchi, MD, of the University of Florence, Florence, Italy, talks about the new models that doctors…

The future of leukemia treatment in the elderly

Acute Lymphoblastic Leukemia 1 Min Read

An advanced age can limit treatment options when tackling leukemia. Speaking from the International Conference on Acute Myeloid Leukaemia 2017,…

When to use bispecifics for AML

Acute Lymphoblastic Leukemia 1 Min Read

As alternatives to chemotherapy are created, the prospect of having treatments with a lower toxicity becomes more tangible. In this…

Expanding trials using bispecifics

Acute Lymphoblastic Leukemia 1 Min Read

This is an exciting time for leukemia research, with the latest research using bispecifics revealing positive outcomes for patients. Here,…

Cytokine release syndrome: a limiting factor for AML treatment

Acute Lymphoblastic Leukemia 1 Min Read

The inflammation induced by medication can create challenges when producing novel treatments. In this interview, Prof. John DiPersio, MD, PhD…

Bispecific agents: the future of AML and MDS treatment?

Acute Lymphoblastic Leukemia 1 Min Read

It is crucial that drug toxicity is kept as low as possible to improve the quality of life of patients.…

The problem of treating AML with CD123-targeting drugs

Acute Lymphoblastic Leukemia 1 Min Read

As diseases mutate our knowledge of them increases. In this interview, Prof. John DiPersio, MD, PhD from Washington University School…

New treatments for AML using inhibitors

Acute Lymphoblastic Leukemia 1 Min Read

This is an exciting time for acute myeloid leukemia (AML) treatment, with multiple new therapies being investigated currently. In this…

The standardization of molecular diagnostics for myeloid diseases in Italy

Acute Lymphoblastic Leukemia 1 Min Read

Using uniform methods of detection allows for the efficient diagnosis of various ailments. In this interview, Francesco Lo-Coco, MD, from…

The use of second generation FLT3 inhibitors for AML

Acute Lymphoblastic Leukemia 1 Min Read

As treatment advancements are made, the number of people who cannot be treated effectively is reduced. In this interview, Francesco…

Mimetics: the future of AML treatment?

Acute Lymphoblastic Leukemia 1 Min Read

When considering which treatment to prescribe for acute myeloid leukemia (AML), an advanced age is a limiting factor. With recent…

Highly targeted medication for AML

Acute Lymphoblastic Leukemia 1 Min Read

There have been large strides in the treatment of leukemia; however, current methods lack specificity. Speaking from the International Conference…

Combating AML

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Wei, MBBS, PhD, FRACP, FRCPA, from Alfred Hospital and Monash University, Melbourne, Australia discusses how a novel molecule, S64315,…

Multiple myeloma: consensuses and controversies

Acute Lymphoblastic Leukemia 1 Min Read

There is some agreement within the multiple myeloma (MM) community regarding the importance of combination chemotherapy, transplant, personalized therapy and…

Current research into pro-apoptosis medication for leukemia

Acute Lymphoblastic Leukemia 1 Min Read

The evasion of apoptosis is a hallmark of cancer, which needs to be halted in order to treat malignancies. In…

Patient care must be considered when using new anticancer drugs

Acute Lymphoblastic Leukemia 1 Min Read

As novel anticancer drugs undergo clinical trials and enter the market, patients with cancer are experiencing better outcomes and living…

The importance of the cancer nurse

Acute Lymphoblastic Leukemia 1 Min Read

Cancer nurses play a critical role in improving the quality of life and outcomes of patients. In this interview, recorded…

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