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Home » Page 32

Ongoing Randomized Studies of Selinexor – Selinexor with chemotherapy, single-agent activity, etc

Acute Lymphoblastic Leukemia 1 Min Read

Michael Kauffman, MD and CEO from Karyopharm Therapeutics Inc discusses ongoing randomized studies of Selinexor and Selinexor with chemotherapy, single-agent…

CAR-T Cell Therapy with Diffuse Large-B-cell Lymphoma More CAR-T Cell products available in the near future

Acute Lymphoblastic Leukemia 1 Min Read

John M Burke, MD from Rocky Mountain Cancer Centers discusses CAR-T cell therapy with diffuse Large-B-cell Lymphoma and more CAR-T…

Further Immunotherapy Research in 2018-19 – Incorporate new drugs for newly diagnosed patients with ALL

Acute Lymphoblastic Leukemia 1 Min Read

Stephen Hunger, MD from Children’s Hospital of Philadelphia discusses further immunotherapy research in 2018-19 and the incorporation of new drugs…

Lymphoid Malignancies Treatment Developments – Replacement of Bleomycin with Brentuximab Vedotin

Acute Lymphoblastic Leukemia 1 Min Read

John M Burke, MD from Rocky Mountain Cancer Centers discusses lymphoid malignancies treatment developments and replacement of Bleomycin with Brentuximab…

Developments of Phase 3 Trial: BOSTON Bortezomib in combination with Selinexor for treating Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Michael Kauffman, MD and CEO from Karyopharm Therapeutics Inc discusses developments of Phase 3 trial: BOSTON – Bortezomib in combination…

Patients with Philadelphia Chromosome+ ALL Can Be Cured – Limited use of stem-cell transplants on 1st remission

Acute Lymphoblastic Leukemia 1 Min Read

Stephen Hunger, MD from Children’s Hospital of Philadelphia discusses patients with Philadelphia Chromosome+ ALL can be cured and limited use…

New Phase 3 Murano Trial for CLL – Venetoclax & Rituximab superior to Bendamustine & Rituximab

Acute Lymphoblastic Leukemia 1 Min Read

John M Burke, MD from Rocky Mountain Cancer Centers discusses new Phase 3 Murano trial for CLL and Venetoclax &…

Individualized Medicine in 2018 – Therapies based on tumor specimens, incorporation of patient input

Acute Lymphoblastic Leukemia 1 Min Read

Ruben Mesa, MD from UT Health San Antonio Cancer Center discusses individualized medicine in 2018 and therapies based on tumor…

Monitor Patients Minimal Residual Disease Status – Maintenance doses of obinutuzumab & atezolizumab

Acute Lymphoblastic Leukemia 1 Min Read

John M Burke, MD from Rocky Mountain Cancer Centers discusses monitor patients minimal residual disease status and maintenance doses of…

Successor Trials from North American and European Group – Testing imatnib with chemotherapy backbones

Acute Lymphoblastic Leukemia 1 Min Read

Stephen Hunger, MD from Children’s Hospital of Philadelphia discusses successor trials from North American and European group and testing imatnib…

Selinexor is Mechanism of Action It restores the activity of tumor-suppressant proteins

Acute Lymphoblastic Leukemia 1 Min Read

Michael Kauffman, MD and CEO from Karyopharm Therapeutics Inc discusses Selinexor its mechanism of action and as it restores the…

New Oral Compound, Selinexor – Selinexor can be safely combined with different drugs for efficacy

Acute Lymphoblastic Leukemia 1 Min Read

Michael Kauffman, MD and CEO from Karyopharm Therapeutics Inc discusses a new oral compound, Selinexor and how it can be…

New Study with Diffuse Large B-Cell Lymphoma – Improvements taking Polatuzumab with Bendamustine and Rituximab

Acute Lymphoblastic Leukemia 1 Min Read

John M Burke, MD from Rocky Mountain Cancer Centers discusses a new study with diffuse large B-cell lymphoma and improvements…

Subgroups of Patients who Benefit from Interferon – Delaying progression or progression-free survival

Acute Lymphoblastic Leukemia 1 Min Read

Ruben Mesa, MD from UT Health San Antonio Cancer Center discusses subgroups of patients who benefit from interferon and delaying…

High-Response Rates from both Selinexor and Velcade The combination of the two show synergy against Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Michael Kauffman, MD and CEO from Karyopharm Therapeutics Inc discusses high-response rates from both Selinexor and velcade and the combination…

Phase 2 Trial of Dasatinib with Philadelphia Chromosome+ ALL – Results were similar to studies with imatnib

Acute Lymphoblastic Leukemia 1 Min Read

Stephen Hunger, MD from Children’s Hospital of Philadelphia discusses Phase 2 trial of dasatinib with Philadelphia Chromosome+ ALL and the…

Use of Rituximab after Bendamustine is Relatively Safe

Acute Lymphoblastic Leukemia 1 Min Read

John M. Burke, MD from Rocky Mountain Cancer Centers discusses use of rituximab after bendamustine is relatively safe at the…

Impact of Immune-based Therapies – Great impact on lymphoid malignancies

Acute Lymphoblastic Leukemia 1 Min Read

Ruben Mesa, MD from UT Health San Antonio Cancer Center discusses impact of immune-based therapies and great impact on lymphoid…

Additional Combinations with Selinexor – Pomalidomide, Revlimid, Daratumumab

Acute Lymphoblastic Leukemia 1 Min Read

Michael Kauffman, MD from Karyopharm Therapeutics Inc discusses additional combinations with Selinexor & pomalidomide, revlimid, daratumumab at the 2017 American…

EsPhALL Regimen – Adding Dasatnib to Intensive Chemotherapy Backbone

Acute Lymphoblastic Leukemia 1 Min Read

Stephen Hunger, MD from Children’s Hospital of Philadelphia discusses EsPhALL regimen and adding Dasatnib to intensive chemotherapy backbone at the…

Multiple Myeloma Study – Added daratumumab towards CD38

Acute Lymphoblastic Leukemia 1 Min Read

John M. Burke, MD from Rocky Mountain Cancer Centers discusses multiple myeloma study and added daratumumab towards CD38 at the…

Chemo-Immunotherapy in Non-Squamous NSCLC: Has the KEYNOTE-189 Trial Defined a Clear Standard of Care? (BMIC-022)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West reviews the results and pending questions of the KEYNOTE-189 trial of chemotherapy with or without pembrolizumab (KEYTRUDA)…

Who Should Get PRRT?

Acute Lymphoblastic Leukemia 1 Min Read

Soulen – Who Should Get PRRT Weighing Cumulative Toxicity Key to PRRT Treatment Michael C. Soulen, MD of the University…

Primary Resection of Tumor in Gut No Survival Difference Between Resected and Non-Resected

Acute Lymphoblastic Leukemia 1 Min Read

Michael C. Soulen, MD of the University of Pennsylvania discusses primary resection of tumor in the gut and how there…

Peptide Receptor Radionuclide Therapy US Approval Expected Early 2018

Acute Lymphoblastic Leukemia 1 Min Read

Michael C. Soulen, MD of the University of Pennsylvania discusses that peptide receptor radionuclide therapy US approval expected early 2018…

Is PRRT Practice Changing?

Acute Lymphoblastic Leukemia 1 Min Read

Michael C. Soulen, MD of the University of Pennsylvania answers the question “Is PRRT Practice Changing?”. He summarizes that cost,…

The adoption of biosimilars in Oxford: a case study

Acute Lymphoblastic Leukemia 1 Min Read

Identifying the optimal means of introducing biosimilars is an issue facing all clinics. Biosimilar rituximab was introduced in Oxford, UK…

Biosimilar benefits: cost saving in the NHS

Acute Lymphoblastic Leukemia 1 Min Read

Biosimilar licensing represents a huge opportunity for the NHS to make vital cost savings. In this interview, recorded at the…

Improving the NICE drug approval process

Acute Lymphoblastic Leukemia 1 Min Read

In this interview, Ms Man-Chie Chow from the Royal Surrey County Hospital, Guildford, UK gives a brief overview of the…

Mind the gap! Drug funding and access

Acute Lymphoblastic Leukemia 1 Min Read

The method of how new medication is determined to be cost-effective serves a crucial role in drug access. Here, Ms…

Analyzing the affordability of additional multiple myeloma drugs

Acute Lymphoblastic Leukemia 1 Min Read

Affordable treatment reduces the burden on the healthcare services and increases the chances of NICE approval. Speaking from the British…

Streamlining the administrative burden of drug price agreements for pharmacists

Acute Lymphoblastic Leukemia 1 Min Read

Streamlining the administration process of drug price agreements can greatly reduce the labor of pharmacists. In this interview at the…

Identifying Minimum Residual Disease Flow Cytometry, Next Gen Sequencing in Multiple Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Damian J. Green, MD, from Seattle Cancer Care Alliance discusses Identifying Minimum Residual Disease using Flow Cytometry and Next Gen…

Role of Tandem Autologous Transplant PFS and Overall Survival in Multiple Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Damian J. Green, MD, from Seattle Cancer Care Alliance discusses the Role of Tandem Autologous Transplant and PFS and Overall…

Radiolabeled CD45 in Stem Cell Transplant For High Risk Multiple Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Damian J. Green, MD, from Seattle Cancer Care Alliance discusses Radiolabeled CD45 in Stem Cell Transplant For High Risk Multiple…

New Trial CAR T-Cells Targeting BCMA For Multiple Myeloma using Human Anti-BCMA

Multiple Myeloma 1 Min Read

Damian J. Green, MD, from Seattle Cancer Care Alliance discusses a New Trial CAR T-Cells Targeting BCMA For Multiple Myeloma…

Allogeneic Stem Cell Transplant with Busulfan Possible PFS in Multiple Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Damian J. Green, MD, from Seattle Cancer Care Alliance discusses how Allogeneic Stem Cell Transplant with Busulfan may Possibly improve…

Small molecule inhibitors for CLL: which to use, sequencing, switching and combinations

Acute Lymphoblastic Leukemia 1 Min Read

There are now three small molecule inhibitors to choose from for the treatment of chronic lymphocytic leukemia (CLL): Ibrutinib, idelalisib…

Should standard chemotherapy regimens be altered in favor of small molecules? iFCG for frontline CLL

Acute Lymphoblastic Leukemia 1 Min Read

With many promising novel therapeutic agents exiting pharmaceutical pipelines, a question that arises is whether standard chemotherapy regimens with long-term…

Novel BTK inhibitor acalabrutinib shows promise in CLL

Acute Lymphoblastic Leukemia 1 Min Read

A novel BTK inhibitor, acalabrutinib, is showing promise in the early clinical trial stages for chronic lymphocytic leukemia (CLL). Speaking…

Small molecule-chemotherapy combinations: ibrutinib plus rituximab for CLL

Acute Lymphoblastic Leukemia 1 Min Read

Antibody-chemotherapy combinations are a standard treatment for hematological malignancies, and with an increase in small molecules coming through the pharmaceutical…

Elderly ALL advances: inotuzumab ozogamicin plus mini-hyper-CVD

Acute Lymphoblastic Leukemia 1 Min Read

Older patients with acute lymphoblastic leukemia (ALL) have significantly worse outcomes; thus, there is a great need for improved treatments…

Safety data for the PI3K? inhibitor umbralisib for lymphoid malignancies

Acute Lymphoblastic Leukemia 1 Min Read

In this interview, Susan OBrien, MD, of the University of California, Irvine, CA, talks to us about the next-generation PI3K?…

MRD assessment: NGS vs. flow cytometry

Acute Lymphoblastic Leukemia 1 Min Read

One of the controversies surrounding the use of minimal residual disease (MRD) is the optimal technique for its assessment. Speaking…

MRD-guided high-dose carfilzomib treatment for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

The use of minimal residual disease (MRD) status in the clinic and trials is a promising, yet controversial, area of…

CENTAURUS trial: daratumumab monotherapy for smoldering multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

The treatments available for smoldering multiple myeloma (MM) are limited, with typical recommendations of observation or enrollment in clinical trials.…

Overcoming the limits to widespread NGS implementation

Acute Lymphoblastic Leukemia 1 Min Read

Next-generation sequencing (NGS) has been widely used in research for the past decade or more; however, its translation into the…

The story behind targeting FLT3 in AML and the next generation of inhibitors

Acute Lymphoblastic Leukemia 1 Min Read

When FLT3 inhibitors were first on the horizon, expectations were high, with hopes that they would have a similar level…

The future of AML treatment? Progress in IDH1/2 inhibitors for AML

Acute Lymphoblastic Leukemia 1 Min Read

The development of IDH inhibitors for acute myeloid leukemia (AML) has been a smoother journey than that for FLT3 inhibitors.…

Genetic heterogeneity in AML: the reasoning behind targeting FLT3 and IDH

Acute Lymphoblastic Leukemia 1 Min Read

Researchers and clinicians now recognize that AML comprises a multitude of subtypes. In this interview, Richard Stone, MD, of the…

AML: data to look forward to in 2018 and beyond

Acute Lymphoblastic Leukemia 1 Min Read

In this interview, Richard Stone, MD, of the Dana-Farber Cancer Institute, Boston, MA, gives his forecast of the acute myeloid…

Overview of the RATIFY study: midostaurin combination therapy for AML

Acute Lymphoblastic Leukemia 1 Min Read

In this interview, Richard Stone, MD, of the Dana-Farber Cancer Institute, Boston, MA, provides an overview of the Phase III…

Support Group Leader%27s Perspective – Robin Tuohy

Acute Lymphoblastic Leukemia 1 Min Read

Patients Perspective- Cindy Chmielewski

Acute Lymphoblastic Leukemia 1 Min Read

ASH 2017- Patient%27s Perspective – John DeFlice%2C MD

Acute Lymphoblastic Leukemia 1 Min Read

Phase III Trial for Multiple Myeloma – Busulfan + Melphalan Vs Melphalan Alone

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD, from MD Anderson Cancer Center discusses Phase III Trial for multiple myeloma and Busulfan + Melphalan…

ZUMA-1 Trial Long Term Follow Up – Very Few Long Term Safety Signals

Acute Lymphoblastic Leukemia 1 Min Read

Sattva S. Neelapu, MD from MD Anderson Cancer Center discusses ZUMA-1 trial long term follow up and very few long…

Phase II Study in Multiple Myeloma Combination of Lenalidomide-Elotuzumab

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD, from MD Anderson Cancer Center discusses the phase II study in multiple myeloma and the combination…

Risks of Toxicity with Interferon – Chronic low-grade toxicities with the therapy

Acute Lymphoblastic Leukemia 1 Min Read

Ruben Mesa, MD, from UT Health San Antonio Cancer Center discusses risks of toxicity with interferon and chronic low-grade toxicities…

Mechanics of CAR-T Cell Therapy – Combining axi-cel with an anti-PDL1 antibody

Acute Lymphoblastic Leukemia 1 Min Read

Sattva S. Neelapu, MD from MD Anderson Cancer Center discusses mechanics of CAR-T cell therapy and combining axi-cel with an…

Immunoactive Treatments – Bispecific antibodies, CAR-T Cells, and monovalent antibodies

Acute Lymphoblastic Leukemia 1 Min Read

Gareth Morgan, MD, from University of Arkansas for Medical Sciences discusses immunoactive treatments and bispecific antibodies, CAR-T cells, and monovalent…

Myeloma drugs for 2018 – Anti-body drug conjugates, Bi-specific T-cell engagers, etc.

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD, PhD, from MD Anderson Cancer Center discusses myeloma drugs for 2018 and anti-body drug conjugates, Bi-specific…

The new chemotherapy combination works better than previous – Information to be disseminated soon, awaits approval by regulators

Acute Lymphoblastic Leukemia 1 Min Read

Joseph M. Connors, MD from British Colombia Cancer Agency discusses the new chemotherapy combination works better than previous and information…

FDA Approval of Axi-Cel – 42% of patients have long-term durability

Acute Lymphoblastic Leukemia 1 Min Read

Sattva S. Neelapu, MD from MD Anderson Cancer Center discusses FDA’s approval of Axi-Cel and 42% of patients have long-term…

Pegylated Interferon Alfa-2a – Utilization of Interferon on patients with MPN is still limited

Acute Lymphoblastic Leukemia 1 Min Read

Ruben Mesa, MD from UT Health San Antonio Cancer Center discusses Pegylated Interferon Alfa-2a and the utilization of Interferon on…

Safety for the 1st Cycle of CyBorD – Decreases infusion time from 7 hrs. to 4.3 hours

Acute Lymphoblastic Leukemia 1 Min Read

Habte Yimer, MD from Texas Oncology discusses safety for the 1st cycle of CyBorD and how it decreases infusion time…

The Importance of Prognosis on Oncology – Probability of outcome of disease is useful for patients and physicians

Acute Lymphoblastic Leukemia 1 Min Read

Aziz Nazha, MD from Cleveland Clinic discusses the importance of prognosis on oncology and the probability of outcome of disease…

Ixazomib for Maintenance In Multiple Myeloma – Ixazomib maybe approved by the FDA after trials

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD from MD Anderson Cancer Center discusses Ixazomib for maintenance in multiple myeloma and Ixazomib maybe approved…

Double-Hit Myeloma – Bialellic activation of P-53, ISS Stage 3, amplification of chromosome 1Q

Acute Lymphoblastic Leukemia 1 Min Read

Gareth Morgan, MD from University of Arkansas for Medical Sciences discusses double-hit myeloma and bialellic activation of P-53, ISS stage…

Dr. Peter Lucas discusses clinical trial testing

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Peter Lucas, Director of Laboratory Services & Principal Investigator at NSABP, discusses clinical trial testing.

Phase 2 Study of Daratumumab – Assess good, partial, or better response after 4 cycles

Acute Lymphoblastic Leukemia 1 Min Read

Habte Yimer, MD from Texas Oncology discusses Phase 2 study of Daratumumab and assess good, partial, or better response after…

Developments with immunotherapy and lymphoid malignancies – Checkpoint Inhibitors and immune system manipulation

Acute Lymphoblastic Leukemia 1 Min Read

Joseph M. Connors, MD from British Colombia Cancer Agency discusses developments with immunotherapy and lymphoid malignancies – Checkpoint inhibitors and…

Rituximab After Bendamustine – Rituximab Maintenance Improved PFS

Acute Lymphoblastic Leukemia 1 Min Read

John M. Burke, MD from Rocky Mountain Cancer Centers discusses Rituximab after Bendamustine – Rituximab maintenance improved PFS at the…

CAR-T Cell Therapy in Large Cell Lymphoma – 80 response rate with 50 complete remission

Acute Lymphoblastic Leukemia 1 Min Read

Sattva S. Neelapu, MD from MD Anderson Cancer Center discusses CAR-T cell therapy in large cell Lymphoma – 80 response…

Can MRD Negative Patients Stop Maintenance – Continue treatment until the time of progression

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD from MD Anderson Cancer Center discusses if MRD negative patients can stop maintenance and continue treatment…

Daratumumab Studies have Shown Significant Benefits – Effective in combination with CyBorD

Acute Lymphoblastic Leukemia 1 Min Read

Habte Yimer, MD from Texas Oncology discusses Daratumumab studies have shown significant benefits and effective in combination with CyBorD at…

Developing Data will Help Clinicians – CAR-T Cells are going to be very effective for Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Gareth Morgan, MD from University of Arkansas for Medical Sciences discusses developing data will help clinicians and CAR-T cells are…

MPD-RC 111 Protocol For Patients with Polycythemia Vera or Essential Thrombocythemia

Acute Lymphoblastic Leukemia 1 Min Read

Ruben Mesa, MD from UT Health San Antonio Cancer Center discusses MPD-RC 111 protocol for patients with polycythemia vera or…

Digital disease tracking: the uMotif app for symptom-tracking

Acute Lymphoblastic Leukemia 1 Min Read

Personal digital disease tracking enables patients and the multidisciplinary team managing their care to better monitor their disease. Speaking from…

Promising results from the pilot study of the uMotif app for CRC

Acute Lymphoblastic Leukemia 1 Min Read

Digital technologies can aid both patients and clinicians in managing a disease. Here, Nina Paton from The Christie NHS Foundation…

Multidisciplinary cancer research: overcoming the odds

Acute Lymphoblastic Leukemia 1 Min Read

There is a lack of funding for research into certain cancer types, such as lung and pancreatic cancer, compared with…

The role of pharmacists in utilizing novel pancreatic cancer treatments

Acute Lymphoblastic Leukemia 1 Min Read

Speaking from the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium 2017 in Glasgow, UK, Islam Elkonaissi of The Royal…

Clinical update: lung and pancreatic cancer

Acute Lymphoblastic Leukemia 1 Min Read

Exciting clinical updates for lung and pancreatic cancer were presented at the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium…

HCC under the microscope: From bench to bedside

Acute Lymphoblastic Leukemia 1 Min Read

In this presentation from the ‘Looking Closely at New Therapeutic Options for Hepatocellular Carcinoma’, Dr. Bruno Daniele discusses the latest…

New treatment approaches for advanced, unresectable HCC

Acute Lymphoblastic Leukemia 1 Min Read

In this presentation from the ‘Looking Closely at New Therapeutic Options for Hepatocellular Carcinoma’, Dr. Jordi Bruix discusses novel treatment…

New developments in locoregional treatments for HCC

Acute Lymphoblastic Leukemia 1 Min Read

In this presentation from the ‘Looking Closely at New Therapeutic Options for Hepatocellular Carcinoma’, Dr. Luigi Bolondi discusses the latest…

Progress has been made combatting Hodgkins lymphoma – A more effective recipe new analyses and insights for treatments

Acute Lymphoblastic Leukemia 1 Min Read

Joseph M. Connors, MD from British Colombia Cancer Agency discusses the progress that has been made combatting Hodgkins lymphoma and…

Further research in Multiple Myeloma – Adapting to a minimal residual disease driven approach

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD from MD Anderson Cancer Center discusses further research in Multiple Myeloma and adapting to a minimal…

New Conjugate CD 79 – Relapsed Refractory B-Cell

Acute Lymphoblastic Leukemia 1 Min Read

John M. Burke, MD from Rocky Mountain Cancer Centers discusses new conjugate CD 79 and relapsed refractory B-Cell at the…

Predicting Survival Myelodysplastic Syndrome – Using the Random Survival Forest Algorithm

Acute Lymphoblastic Leukemia 1 Min Read

Aziz Nazha, MD from the Cleveland Clinic discusses predicting Survival Myelodysplastic Syndrome and using the Random Survival Forest Algorithm at…

Studies in 2018 – CASSINI and Apixaban for the prevention of VTE

Acute Lymphoblastic Leukemia 1 Min Read

Alok Khorana, MD from the Cleveland Clinic discusses studies in 2018 and CASSINI and Apixaban for the prevention of VTE…

Beyond ZUMA-1 Evaluating Axi-Cel efficacy

Acute Lymphoblastic Leukemia 1 Min Read

Sattva S. Neelapu MD, from MD Anderson Cancer Center discusses beyond ZUMA-1 and evaluating Axi-Cel efficacy at the 2017 American…

Multiple Myeloma studies for 2018 Data from Daratumumab with carfilzomib, lenalidomide etc

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD, PhD, from The University of Texas MD Anderson Cancer Center discusses multiple myeloma studies for 2018…

The future of cancer therapy innovation

Acute Lymphoblastic Leukemia 1 Min Read

The production of novel anti-cancer treatments has taken cancer therapy to a point that was previously unimaginable. Here, Jeff Evans,…

Results of the Echelon-1 Trial New chemotherapy is a combination of brentuximab vedotin, and AVD

Acute Lymphoblastic Leukemia 1 Min Read

Joseph M. Connors, MD from British Colombia Cancer Agency discusses results of the Echelon-1 Trial and new chemotherapy that is…

Partnering with leading UK cancer charities to enhance patient treatment and support

Acute Lymphoblastic Leukemia 1 Min Read

When helping patients through their treatment, CRUK and Macmillan Cancer Support act as fantastic allies for pharmacists. In this interview,…

The evolution of cancer care in community pharmacies

Acute Lymphoblastic Leukemia 1 Min Read

Jackie Lewis, BPharm, MRPharmS, PhD of Lewis Pharmacy, Devon, UK discusses the evolution of cancer care in community pharmacies. Dr…

The importance of pharmacists in clinical trials and therapy delivery

Acute Lymphoblastic Leukemia 1 Min Read

As the demand on healthcare services increases, novel and innovative ways to meet that demand need to be created. In…

Crossing barriers between primary and secondary care for pharmacists

Acute Lymphoblastic Leukemia 1 Min Read

Speaking from the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium 2017 in Glasgow, UK, Jackie Lewis, BPharm, MRPharmS, PhD…

Algorithm Picks Relevant Variables Variables help predict survivability with myelodysplastic syndromes

Acute Lymphoblastic Leukemia 1 Min Read

Aziz Nazha, MD from the Cleveland Clinic discusses algorithm picks relevant variables and variables help predict survivability with myelodysplastic syndromes…

How do we sequence and combine novel agent-based therapies in CLL?

Acute Lymphoblastic Leukemia 1 Min Read

There are now many drugs available for the treatment of chronic lymphocytic leukemia (CLL); however, there is only limited data…

Determining the best course of treatment for younger patients with relapsed/refractory CLL

Acute Lymphoblastic Leukemia 1 Min Read

The optimal treatment for younger patients with relapsed/refractory chronic lymphocytic leukemia (CLL) depends on a number of factors, including what…

Exciting results for frontline ibrutinib plus FCR for younger CLL patients

Acute Lymphoblastic Leukemia 1 Min Read

There are now many effective therapies to choose from for chronic lymphocytic leukemia (CLL). Thus, a recent area of therapeutic…

Strategies for treating RichterÂ’s transformation in CLL: checkpoint inhibitors and venetoclax

Acute Lymphoblastic Leukemia 1 Min Read

Richters transformation remains a challenge in chronic lymphocytic leukemia (CLL). In this interview, Matthew Davids, MD, of the Dana-Farber Cancer…

Atezolizumab + Bendamustine & Obinutuzumab – No major safety signals in follicular lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

John M. Burke, MD from Rocky Mountain Cancer Centers discusses Atezolizumab + Bendamustine & Obinutuzumab and no major safety signals…

Mechanisms of gilteritinib resistance in FLT3-mutated AML

Acute Lymphoblastic Leukemia 1 Min Read

Targeted therapies have revolutionized the treatment of cancer; however, under the selective pressures exerted by these therapies, tumor cells with…

Combining FLT3 and SYK inhibition for AML

Acute Lymphoblastic Leukemia 1 Min Read

TAK-659 is a novel FLT3 inhibitor in the initial trial stages for the treatment of acute myeloid leukemia (AML). Interestingly,…

Molecular genetics and targeting in AML: highlights from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Although our knowledge of the underlying genetic causes of acute myeloid leukemia (AML) and their consequent molecular results has progressed…

Assaying FLT3 variant allele frequency in AML to determine response to treatment

Acute Lymphoblastic Leukemia 1 Min Read

In patients whose cancer is primarily caused by a specific mutation, tests which enable the determination of variant allele frequency…

Combinations Well Tolerated in Multiple Myeloma Benefits are better when compared to lenalidomide alone

Acute Lymphoblastic Leukemia 1 Min Read

Robert Z. Orlowski, MD, PhD, from The University of Texas MD Anderson Cancer Center discusses combinations well tolerated in multiple…

Axi-Cel is a milestone for treating B-Cell Lymphoma Paradigm shift for future B-Cell Lymphoma treatment

Acute Lymphoblastic Leukemia 1 Min Read

Sattva S. Neelapu, MD, from the University of Texas MD Anderson Cancer Center discusses how Axi-Cel is a milestone for…

Prevalence and Consequences of VTE – Increased chance of fatality and admitted to hospital

Acute Lymphoblastic Leukemia 1 Min Read

Alok Khorana, MD of the Cleveland Clinic discusses the prevalence and consequences of VTE and increased chance of fatality and…

Checkpoint Inhibitors in Hodgkin’s Lymphoma – Immune System Manipulation and CAR-T Cells

Acute Lymphoblastic Leukemia 1 Min Read

Joseph M. Connors, MD, FRCPC from The BC Cancer Agency Research Centre discusses checkpoint inhibitors in Hodgkin’s lymphoma and immune…

How advanced cancer imaging methods could revolutionize treatment

Acute Lymphoblastic Leukemia 1 Min Read

Although great strides have been made in cancer treatment and diagnosis, in many types of cancer these aspects are still…

How neural networks help with knowledge discovery in cancer imaging

Acute Lymphoblastic Leukemia 1 Min Read

There is a constant need for new knowledge discovery in cancer biology; we do not yet fully understand the underlying…

The chicken and the egg: processing cancer imaging data so that more can be processed

Acute Lymphoblastic Leukemia 1 Min Read

Modern machinery learning techniques allow for the processing of large quantities of cancer images, at a much faster rate than…

Neural networks and deep learning in cancer imaging analysis

Acute Lymphoblastic Leukemia 1 Min Read

Artificial neural networks that can process information have existed for a long time. However, in recent years greater computing power…

Modern machinery learning techniques in cancer imaging

Acute Lymphoblastic Leukemia 1 Min Read

Although there are few data sets available to researchers in cancer imaging compared with other fields, experts are able to…

Analyzing cancer imaging data from few datasets

Acute Lymphoblastic Leukemia 1 Min Read

When studying patient data, many fields of cancer medicine will have large databases containing information from tens of thousands of…

Heating up a tumor: modulating the immunoscore

Acute Lymphoblastic Leukemia 1 Min Read

The immunoscore is a predictive tool that looks at a cancer patients adaptive immunity to predict survival and recurrence, amongst…

Tracking an immunoscore throughout treatment

Acute Lymphoblastic Leukemia 1 Min Read

An immunoscore is an evaluative test of a cancer patients adaptive immune activity towards their tumor, and can predict survival,…

The current and future uses of the immunoscore

Acute Lymphoblastic Leukemia 1 Min Read

The immunoscore is a predictive tool that scores cancer patients based on an evaluation of their adaptive immunity. In this…

The immunoscore: a new way of stratifying cancer

Acute Lymphoblastic Leukemia 1 Min Read

It is important that we have accurate models for the risk stratification of cancer patients, in order to determine how…

The immunoscore: the most powerful predictor of cancer recurrence and survival

Acute Lymphoblastic Leukemia 1 Min Read

There are many ways of predicting cancer recurrence and survival; these include pathology-based tests, such as tumor grade, molecular markers,…

Presenting the immunoscore

Acute Lymphoblastic Leukemia 1 Min Read

In recent years, the interest of the scientific community in the immune system as it relates to cancer has greatly…

Publication in Practice: Immune Thrombocytopenia Purpura

Acute Lymphoblastic Leukemia 1 Min Read

Knowledge is evolving regarding numerous clinical aspects of immune thrombocytopenia purpura (ITP), and there remains significant variability in clinical practice…

Key Insights in Thoracic Oncology

Acute Lymphoblastic Leukemia 1 Min Read

In this Key Insights activity, Drs. Corey J. Langer, MD and Joshua Bauml discuss the key take-home points from the…

Utility of analyzing formerly fixed tissue samples

Acute Lymphoblastic Leukemia 1 Min Read

Recent developments in research allowing for the DNA analysis of formalin-fixed samples have allowed for greater accessibility to tumor sample…

First steps for the UKÂ’s first high energy proton beam therapy centers

Acute Lymphoblastic Leukemia 1 Min Read

Proton beam therapy is a high energy, localized form of radiation therapy that has the potential to greatly improve the…

Importance of formalin-fixed samples

Acute Lymphoblastic Leukemia 1 Min Read

Recent research has demonstrated that a lot of information about a cancer can be elucidated from a formalin-fixed sample, as…

NHS treating proton beam therapy with due caution

Acute Lymphoblastic Leukemia 1 Min Read

With the NHS opening two high energy proton beam centers next year, optimism is high in the medical community for…

The evolution of proton beam therapy

Acute Lymphoblastic Leukemia 1 Min Read

Even though the UKs first high energy proton beam centers are yet to open, it is critical to look forward…

Why the NHS has timed its investment into proton beam therapy well

Acute Lymphoblastic Leukemia 1 Min Read

The NHS is opening its first two high energy proton beam therapy centers in 2018 and 2020, at great financial…

The importance of BOPA

Acute Lymphoblastic Leukemia 1 Min Read

The dissemination and sharing of scientific knowledge is key to improving healthcare practices on a national and international scale. In…

The introduction of novel immunotherapies and the pharmacist

Acute Lymphoblastic Leukemia 1 Min Read

Novel immunotherapies have great potential to improve the survival of cancer patients; however, new treatments must be introduced in a…

Cancer diagnosis and survival in the UK

Acute Lymphoblastic Leukemia 1 Min Read

The early diagnosis of cancer is key to survival; however, with the many demands upon the NHS this can be…

The CRUK Facilitator programme: from the lab to the clinic

Acute Lymphoblastic Leukemia 1 Min Read

CRUK is well known for scientific research; however, it also employs other channels to transition the results of this research…

The CRUK Facilitator programme and NHS Lanarkshire pharmacists

Acute Lymphoblastic Leukemia 1 Min Read

The CRUK Facilitator programme is collaborating with community pharmacists to provide training and resources. In this interview, Gillian Phillips from…

The CRUK Facilitator programme: collaborating with pharmacists

Acute Lymphoblastic Leukemia 1 Min Read

The earlier cancer is diagnosed, the higher the chance of recovery. At the British Oncology Pharmacy Association (BOPA) 20th Annual…

Update on immunotherapy trials for AML from ASH 2017: bispecific DARTs, CAR T-cells and antibody-drug conjugates

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy for acute myeloid leukemia (AML) is an exciting area, with clinical trials, including those that are first-in-human, showing promising…

Update on venetoclax combination trials for elderly AML from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

There were impressive updates on venetoclax combination studies for elderly acute myeloid leukemia (AML) that are progressing at the American…

Breakthrough E-selectin inhibitor therapy for elderly AML

Acute Lymphoblastic Leukemia 1 Min Read

E-selectin is involved in the progression of acute myeloid leukemia (AML), playing a key role in angiogenesis, thus making it…

Curative strategy for smoldering multiple myeloma: GEM-CESAR

Acute Lymphoblastic Leukemia 1 Min Read

In this exciting interview from the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, Maria-Victoria…

Dual FLT3/SYK oral inhibitor for AML: TAK-659

Acute Lymphoblastic Leukemia 1 Min Read

SYK, which directly binds to and activates FLT3, has been implicated in the pathogenesis of B-cell malignancies, making it a…

Study of the oral FLT3/AXL inhibitor gilteritinib for AML to move forwards

Acute Lymphoblastic Leukemia 1 Min Read

There have been great advances in the targeting of FLT3 for acute myeloid leukemia (AML) in recent years, many of…

Best treatment strategy for FLT3 ITD AML

Acute Lymphoblastic Leukemia 1 Min Read

FLT3 ITD acute myeloid leukemia (AML) is associated with high rates of relapse, after which prognosis is very poor. Thus,…

Recent advances in the targeting of FLT3 in AML

Acute Lymphoblastic Leukemia 1 Min Read

There are now several novel drugs targeting the protein kinase FLT3 in patients with acute myeloid leukemia (AML). Here, Keith…

Ibrutinib and FCR chemoimmunotherapy: improving complete remission in CLL patients?

Acute Lymphoblastic Leukemia 1 Min Read

Recent data have suggested that chronic lymphocytic leukemia (CLL) patients, in particular those with mutated immunoglobulin heavy chain genes, can…

Ibrutinib treatment and its associated risk factors

Acute Lymphoblastic Leukemia 1 Min Read

Ibrutinib is associated with a range of side effects, including increased bruising, TKI ecchymosis, low-grade bleeding and hemorrhage. This has…

CLL updates from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

A range of chronic lymphocytic leukemia (CLL) research was presented at the American Society of Hematology (ASH) 2017 Annual Meeting…

Ibrutinib combination regimens for CLL from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Despite the combination of ibrutinib and rituximab not significantly affecting progression-free survival in patients with chronic lymphocytic leukemia (CLL), many…

Are newer, targeted agents better for the management of untreated CLL than chemoimmunotherapy?

Acute Lymphoblastic Leukemia 1 Min Read

The targeted agent ibrutinib has been tested as a first-line monotherapy in elderly chronic lymphocytic leukemia (CLL) in the RESONATE-2…

Promising results in MDS for ASTX727, an oral decitabine and cytidine deaminase inhibitor agent

Acute Lymphoblastic Leukemia 1 Min Read

Decitabine, a DNA methyltransferase (DNMT) inhibitor, which is given to patients with myelodysplastic syndromes (MDS), is classically administered intravenously. Now,…

May the force be with you: the power of next-generation sequencing

Acute Lymphoblastic Leukemia 1 Min Read

Clinical access to new technologies, such as next-generation sequencing (NGS), can revolutionize the treatment of cancer. In this interview, Guillermo…

Pracinostat for AML update: follow-up analysis and Phase III trial

Acute Lymphoblastic Leukemia 1 Min Read

Pracinostat is a histone deacetylase (HDAC) inhibitor that has demonstrated very promising efficacy in acute myeloid leukemia (AML) and myelodysplastic…

Antagomir for cutaneous T-cell lymphoma: promising trial results

Acute Lymphoblastic Leukemia 1 Min Read

In cutaneous T-cell lymphoma (CTCL) miR-155 has been shown to be upregulated. Here, Christiane Querfeld, MD, PhD, of City of…

Immune checkpoint inhibitors for cutaneous T-cell lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

Immune checkpoint inhibitors have now entered the treatment landscape for cutaneous T-cell lymphoma (CTCL). In this interview, Christiane Querfeld, MD,…

Anti-BCMA CAR T-cells for MM: durable clinical responses with bb2121

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cell therapies have exhibited strong and durable responses in several hematological malignancies thus far. Now bb2121, an anti-BCMA CAR…

Prophylactic treatment for CAR T-cell toxicity shows promising results

Acute Lymphoblastic Leukemia 1 Min Read

For CAR T-cell therapy to become mainstream, the management of related toxicities needs to be addressed. Speaking from the American…

Next-generation CAR T-cell products for 2018

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy for lymphoid malignancies progressed dramatically in 2017, with FDA approval of two CAR T-cell products, axicabtagene ciloleucel and tisagenlecleucel.…

ZUMA-1 trial: FDA approval and follow-up of CAR T-cell product axicabtagene ciloleucel

Acute Lymphoblastic Leukemia 1 Min Read

The Phase I/II trial ZUMA-1 (NCT02348216) was pivotal for CAR T-cell development. In this interview, Yi Lin, MD, PhD, of…

The PRECISION-Panc project: Speeding up scientific discovery to improve pancreatic cancer patient survival

Acute Lymphoblastic Leukemia 1 Min Read

The ground-breaking PRECISION-Panc project aims to speed up scientific discovery to improve the survival rates of patients with pancreatic cancer.…

Upcoming pancreatic cancer study: PRIMUS001

Acute Lymphoblastic Leukemia 1 Min Read

The imminent pancreatic cancer trial PRIMUS001 (ISRCTN75002153) has the potential to personalize therapy for patients with pancreatic cancer. In this…

Pancreatic cancer: The next 10 years

Acute Lymphoblastic Leukemia 1 Min Read

This is an exciting time for pancreatic cancer research, with advances in immunotherapy, genomic sequencing and druggable targets. What the…

The current outlook for pancreatic cancer patients and importance of further research

Acute Lymphoblastic Leukemia 1 Min Read

There is a necessity for further clinical trials and research into pancreatic cancer in order to improve patient outcomes. In…

The current treatment landscape for pancreatic cancer

Acute Lymphoblastic Leukemia 1 Min Read

Although progress has been made in the treatment of pancreatic cancer, further research is required to identify novel therapeutic options…

ASH 2017: New Drugs and Numerous Drug Combinations in Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

How can patients navigate between treatment options with all of the recent breakthroughs in myeloma therapy? Dr. Guilherme Perini, a…

Treatment News in Lymphoma From ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Where is lymphoma treatment today? Stay in the know with Brazilian hematologist Dr. Guilherme Perini as he discusses advances in…

Making Treatment Decisions in Myeloma: How Do I Know WhatÂ’s Right for Me?

Acute Lymphoblastic Leukemia 1 Min Read

The landscape of myeloma care is constantly evolving with the development of new research and treatment. While advances in myeloma…

ROR1: An Update From ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

What have researchers discovered about ROR1 and its role in targeted CLL therapies? Andrew Schorr hosts coverage from the 2017…

ASH 2017: CLL Combination Therapy News

Acute Lymphoblastic Leukemia 1 Min Read

Can todays medicines be used together to treat CLL more effectively? CLL expert Dr. Michael Choi of UC San Diego…

ASH 2017: Are Experts Personalizing Therapy to the Genetics of a PatientÂ’s Myeloma?

Acute Lymphoblastic Leukemia 1 Min Read

Where do things stand now with personalizing myeloma therapy to a patients genetic profile? At the American Society of Hematology…

Follow-up CAR T-cell data so far

Acute Lymphoblastic Leukemia 1 Min Read

The first relatively long-term CAR T-cell trial follow-up data came out at the American Society of Hematology (ASH) 2017 Annual…

Finding the optimal expansion balance: CAR T-cell response markers identified from the trial of JCAR017

Acute Lymphoblastic Leukemia 1 Min Read

The right balance of T-cell expansion needs to be achieved in order to obtain the optimal response to CAR T-cell…

Cytokine storms: CAR T-cell hyperinflammatory response distinct from cytokine release syndrome?

Acute Lymphoblastic Leukemia 1 Min Read

Cytokine release syndrome (CRS) is a relatively well-described toxicity of CAR T-cell therapy. However, their may be delayed manifestations of…

Bispecific CAR T-cell therapy: combining anti-CD19 and CD22 CAR T-cells

Acute Lymphoblastic Leukemia 1 Min Read

With CAR T-cell therapy, similarly to traditional chemotherapy, the use of a single agent will not remain effective in treating…

Anti-CD22 CAR T-cell therapy for ALL: trial update, utility for salvage and CD19 status

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cell therapy development is progressing across a wide range of hematological malignancies, with the results highly anticipated in acute…

New CAR T-cell targeting SLAMF7 shows efficacy against multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

An exciting new CAR T-cell product, which targets SLAMF7 (CS1, CD319), is displaying exciting preliminary results against multiple myeloma (MM)…

Safety profile of anti-CD19 CAR T-cell therapy axicabtagene ciloleucel

Acute Lymphoblastic Leukemia 1 Min Read

A major concern surrounding novel therapeutics is their safety, which must be characterized thoroughly. Here, Sattva Neelapu, MD, from the…

Long-term follow-up results of the ZUMA-1 trial of anti-CD19 CAR T-cells for non-Hodgkin lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

The latest CAR T-cell data was highly anticipated at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition…

CAR T-Cell Therapy Update From ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Chimeric antigen receptor (CAR) T-cell therapy has been receiving buzz as a promising treatment for cancer patients. So which CAR…

What the MPN Experts Learned at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Whats the latest information about MPN treatment and research? As part of our ASH 2017 coverage, Dr. John Crispino and…

ASH 2017: Promising Mantle Cell Lymphoma Treatment News

Acute Lymphoblastic Leukemia 1 Min Read

What does the future of treatment for mantle cell lymphoma look like? From the 2017 American Society of Hematology (ASH)…

CAR T-Cell Therapy News From ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Whats the latest news on CAR-T cell therapy from the American Society Hematology (ASH) conference 2017 as we report on…

An Interferon Update From ASH 2017 From an MPN Expert

Acute Lymphoblastic Leukemia 1 Min Read

As part of our coverage of the 2017 American Society of Hematology (ASH) meeting in Atlanta, Dr. Srdan Verstovsek, an…

ASH 2017 Myeloma Roundtable: Game-Changing Treatment Tools in Myeloma

Acute Lymphoblastic Leukemia 1 Min Read

Will flow be the method used for myeloma treatment in the long term? Does transplant still have a role in…

Updates From ASH 2017: The Latest in Mantle Cell Lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

Whats the latest in mantle cell lymphoma research? Esther Schorr, on location at the 2017 American Society of Hematology (ASH)…

News From ASH 2017: MPN Updates From an Expert Panel

Acute Lymphoblastic Leukemia 1 Min Read

As part of our coverage from the 2017 American Society of Hematology (ASH) annual meeting, A super panel of MPN…

Patient Power ASH Daily Wrap: Day One

Acute Lymphoblastic Leukemia 1 Min Read

Patient Power founders Andrew and Esther Schorr are joined by MPN expert Dr. Naveen Pemmaraju of MD Anderson Cancer Center,…

EGFR Inhibitor Resistant Patients EGFR Antibodies May Play a Role

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center talks about EGFR inhibitor resistant patients and how EGFR antibodies may…

EGFR Small Molecules v Antibodies In Combination Antibodies better than Small Molecules

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center discusses EGFR small molecules versus antibodies in combination antibodies better than…

Oncologic Supplements and Diet Correlative Evidence is Incomplete, Safety First

Acute Lymphoblastic Leukemia 1 Min Read

Jun J. Mao, MD of Memorial Sloan Kettering Cancer Center explains why oncologic supplements and diet correlative evidence is incomplete…

FLAURA Data & Osimertinib High PFS as Front-Line Agent

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center discusses how the FLAURA data & Osimertinib result in high PFS…

Active Patients Equal Better Prognosis and Physically Fit Lung Cancer Patience See Better Outcomes

Acute Lymphoblastic Leukemia 1 Min Read

Jun J. Mao, MD of Memorial Sloan Kettering Cancer Center discusses how physical activity and fitness help lung cancer patients…

American Cancer Society 2015 Lung Cancer Screening Only 300,000 Patients Screened Per Year

Acute Lymphoblastic Leukemia 2 Mins Read

Jim L. Mulshine, MD of Rush University talks about the 2015 lung cancer screening data from the American Cancer Society,…

Engaging Patient in End of Life Care Data Suggest Less Cost

Acute Lymphoblastic Leukemia 1 Min Read

Jennifer S. Temel, MD of Mass General Hospital – Harvard Medical School explains how engaging patients talk about end of…

Lung Cancer EGFR Antibodies Where is the research going?

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center discusses lung cancer EGFR antibodies and where the research is going.…

Definition of Integrative Oncology Means Natural Products, Mind Body and Lifestyle Changes

Acute Lymphoblastic Leukemia 1 Min Read

Jun J. Mao, MD of Memorial Sloan Kettering Cancer Center discusses the definition of integrative oncology which they published a…

Computed Tomography Not Just For Lung Cancer Screening

Acute Lymphoblastic Leukemia 2 Mins Read

Jim L. Mulshine, MD of Rush University talks about computed tomography which can be used not just for lung cancer…

First PET Scan Lung Cancer Scan Nodules Over 8 mm

Acute Lymphoblastic Leukemia 1 Min Read

Daniel A. Pryma, MD of the University of Pennsylvania highlights one common question – when should a patient have his…

Involving Palliative Specialist Earlier Patient Twice as Likely to Discuss End Of Life

Acute Lymphoblastic Leukemia 1 Min Read

Jennifer S. Temel, MD of Mass General Hospital – Harvard Medical School discusses how involving palliative care earlier in the…

Resistance to Osimertinib to create a Flurry of Activity To Find Out Why in 2018

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center talks about possible flurry of activity that focuses on resistance to…

Integrative Medicine Improve Health, Quality of Life, and Clinical Outcomes Oncology Goals

Acute Lymphoblastic Leukemia 1 Min Read

Jun J. Mao, MD of Memorial Sloan Kettering Cancer Center discusses how integrative medicine can improve health, quality of life,…

Costs of New Lung Cancer Services Aging Population Burdening Current Resources

Acute Lymphoblastic Leukemia 2 Mins Read

Jim L. Mulshine, MD of Rush University discusses costs of new lung cancer services and the aging population burdening current…

Cobas EGFR Mutation Test v2 Ability to Sample Patients for T790 Serially

Acute Lymphoblastic Leukemia 1 Min Read

Paul K. Paik, MD of Memorial Sloan Kettering Cancer Center discusses Cobas EGFR mutation test v2 and the ability to…

Most Patients Prefer to Die At Home Honest and Open Communication is Key

Acute Lymphoblastic Leukemia 1 Min Read

Jennifer S. Temel, MD of Mass General Hospital – Harvard Medical School discusses how most patients prefer to die at…

Screening for EGFR Mutation, All Lung Cancer Should Be Screened

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center discusses screening for EGFR mutation and why all lung cancers should…

Integrative Oncology Complementary Therapy May Be Beneficial

Acute Lymphoblastic Leukemia 1 Min Read

Jun J. Mao, MD of Memorial Sloan Kettering Cancer Center discusses integrative oncology and how complementary therapy may be beneficial.…

National Lung Screening Trial More Diverse Population Than Perceived

Acute Lymphoblastic Leukemia 1 Min Read

Jim L. Mulshine, MD of Rush University explains that the national lung screening trial had a more diverse population than…

PFS of FLAURA Trial 18 Months Compared to 1st Gen TKIs

Small Cell Lung Cancer 2 Mins Read

Paul K. Paik, MD of Memorial Sloan Kettering Cancer Center discusses the PFS of FLAURA trial compared to first generation…

Fluorodeoxyglucose (FDG) PET Still Powerful Tool for Lung Cancer

Acute Lymphoblastic Leukemia 1 Min Read

Daniel A. Pryma, MD of the University of Pennsylvania discusses how fluorodeoxyglucose (FDG) PET scan is still powerful tool for…

Patient Prognosis Perception Impacts Medical Care and Quality of Life

Acute Lymphoblastic Leukemia 1 Min Read

Jennifer S. Temel, MD of Mass General Hospital – Harvard Medical School discusses patient prognosis perception and how it impacts…

Squamous Cell Carcinoma 4+ EGFR Carboplatin Cetuximab Safely or Bevacizumab

Acute Lymphoblastic Leukemia 1 Min Read

Roy S. Herbst, MD, PhD of Yale Cancer Center discusses squamous cell carcinoma 4+ EGFR and giving carboplatin cetuximab safely…

Study: Yoga May Benefit Cancer Patients In Combination with Chemotherapy & Improved QOL

Acute Lymphoblastic Leukemia 1 Min Read

Jun J. Mao, MD of Memorial Sloan Kettering Cancer Center discusses a study where yoga may benefit cancer patients in…

Veterans Administration Lung Cancer Pilot Study 40% Of Scans Were of Poor Technical Quality

Acute Lymphoblastic Leukemia 1 Min Read

Jim L. Mulshine, MD of Rush University discusses the veterans administration’s lung cancer pilot study that about 40% of scans…

Squamous Cell Carcinoma Is There Hope?

Acute Lymphoblastic Leukemia 2 Mins Read

Paul K. Paik, MD of Memorial Sloan Kettering Cancer Center discusses that there is short-term and long-term hope for squamous…

Imaging Immunotherapy and Lung Cancer

Acute Lymphoblastic Leukemia 1 Min Read

Daniel A. Pryma, MD of the University of Pennsylvania discusses the challenges of imaging immunotherapy for lung cancer. In the…

Prognosis, Treatment Goals & End of Life Should Not Be Viewed as One Time Conversations

Acute Lymphoblastic Leukemia 1 Min Read

Jennifer S. Temel, MD of Mass General Hospital – Harvard Medical School discusses how prognosis, treatment goals and how end…

Overcoming the limits: bringing CAR T-cell therapy to the masses

Acute Lymphoblastic Leukemia 1 Min Read

The stimulating area of CAR T-cell therapy is currently limited due to a range of factors, which must be overcome…

Take-home message on CAR T-cell therapy for lymphoma from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

The efficacy results of the major CAR T-cells in development have been very positive. In this interview, Jeremy Abramson, MD,…

How services outside of primary and secondary care settings can help cancer patientÂ’s treatment

Acute Lymphoblastic Leukemia 1 Min Read

The assistance obtained from outside of GP clinics and hospitals is essential in the treatment of cancer patients. In this…

How pharmacists and patients can effectively use Macmillan Cancer Support

Acute Lymphoblastic Leukemia 1 Min Read

Supportive care is an essential element of the overall management of patients with cancer. Speaking from the British Oncology Pharmacy…

Selecting the best abstracts for presentation at BOPA

Acute Lymphoblastic Leukemia 1 Min Read

Carl Booth, MPhil BPharm MRPharmS, of Airedale NHS Foundation Trust, Keighley, UK provides an overview of the abstract selection process…

BOPA 2017: What are the hot topics?

Acute Lymphoblastic Leukemia 1 Min Read

Carl Booth, MPhil BPharm MRPharmS, of Airedale NHS Foundation Trust, Keighley, UK talks to us about the key topics presented…

PharmacistsÂ’ collaborations equaling larger and better drug treatment results

Acute Lymphoblastic Leukemia 1 Min Read

Carl Booth, MPhil BPharm MRPharmS, of Airedale NHS Foundation Trust, Keighley, UK, talks to us about collaboration amongst pharmacists to…

Are There Vaccine Recommendations for Patients With MPNs?

Acute Lymphoblastic Leukemia 1 Min Read

In this Ask the Expert segment, a Patient Power community member wants to know Are there recommendations for vaccines for…

How Do I Manage My Risk for Clotting As I Age With Essential Thrombocythemia (ET)?

Acute Lymphoblastic Leukemia 1 Min Read

During this Ask the Expert segment, a community member with essential thrombocythemia (ET) wants to know about increased risk for…

Is There a Role for CAR T-Cell Therapy in MPNs?

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Abdulraheem Yacoub explains how CAR-T cell therapy targets cancer cells in the body and what the future holds for…

Driving efficiency improvements in the NHS

Acute Lymphoblastic Leukemia 1 Min Read

The ways in which healthcare providers function must change to keep up with increasing demand. In this video, Bryn Thomas…

The developing role of pharmacist prescribers

Acute Lymphoblastic Leukemia 1 Min Read

Communicating and learning from shared experiences aids in the improvement of medical practices. In this interview, Bryn Thomas of The…

The potential for patient-level data in the NHS

Acute Lymphoblastic Leukemia 1 Min Read

In todays digitally advanced society, large volumes of patient-level data can be collected and compiled. With an ever-increasing demand upon…

Changing treatment landscapes, new challenges for hemonc pharmacists

Acute Lymphoblastic Leukemia 1 Min Read

How is the role of the pharmacist changing as treatments in hematological cancers develop? Susannah Koontz Webb, PharmD, BCOP, FHOP,…

When BOPA met HOPA: collaborations in oncology pharmacy

Acute Lymphoblastic Leukemia 1 Min Read

Susannah Koontz Webb, PharmD, BCOP, FHOP, President of the Hematology Oncology Pharmacy Association (HOPA) discusses her session on Collaborative Projects…

What is HOPA doing for pharmacists and cancer patients

Acute Lymphoblastic Leukemia 1 Min Read

During the British Oncology Pharmacy Association (BOPA) 20th Annual Symposium 2017 in Glasgow, UK, we met with Susannah Koontz Webb,…

An audit of infusion-related reactions with biosimilar rituximab in London

Acute Lymphoblastic Leukemia 1 Min Read

An important question regarding the use of biosimilar rituximab is whether rapid infusion rates are safe, as they are for…

Integrating cellular therapies into clinical practice

Acute Lymphoblastic Leukemia 1 Min Read

David Irvine from the Beatson Institute, Glasgow, UK discusses introducing CAR-T cells and other cellular therapies into clinical practice and…

Major breakthroughs in AL amyloidosis treatment from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Several major breakthroughs in the treatment of amyloid light-chain (AL) amyloidosis were presented at the American Society of Hematology (ASH)…

Paradigm-changing CAR T-cell therapy for multiple myeloma

Acute Lymphoblastic Leukemia 1 Min Read

This is an exciting time in hemeonc, with new treatment paradigms across a range of malignant hematologies, including multiple myeloma…

Upfront ASCT for newly diagnosed multiple myeloma: double vs. single transplant

Acute Lymphoblastic Leukemia 1 Min Read

The use of frontline autologous stem cell transplantation (ASCT) for newly diagnosed multiple myeloma (MM) has been questioned due to…

Clinical translation of carfilzomib trial data for MM treatment

Acute Lymphoblastic Leukemia 1 Min Read

The proteasome inhibitor carfilzomib has been investigated for the treatment of relapsed/refractory multiple myeloma (MM) in two Phase III clinical…

Results of the ASPIRE trial for MM: the addition of carfilzomib

Acute Lymphoblastic Leukemia 1 Min Read

The American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA presented exciting results from the ASPIRE…

BTK inhibitors for relapsed mantle cell lymphoma: the new standard of care?

Acute Lymphoblastic Leukemia 1 Min Read

The American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, presented exciting data on the use…

Treating lymphoma beyond progression

Acute Lymphoblastic Leukemia 1 Min Read

Treating cancer beyond progression is an important option to be considered in cases where the benefits outweigh the risks. Speaking…

ECHELON-1 trial data from ASH 2017: controversies and clinical translation

Acute Lymphoblastic Leukemia 1 Min Read

An update on the results of the Phase III ECHELON-1 study (NCT01712490), comparing ABVD vs. AVD plus brentuximab vedotin in…

CAR T-cells for lymphoma: data from ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cells are a particularly exciting therapeutic area, which was widely covered at the American Society of Hematology (ASH) 2017…

New antibody-drug conjugates for lymphoma

Acute Lymphoblastic Leukemia 1 Min Read

Following on from the success of brentuximab vedotin, new antibody-drug conjugates (ADCs) for lymphoma are on the horizon. These successors…

PV Reporter Interviews Dr. Jean Jacques Kiladjian at ASH 2017

Acute Lymphoblastic Leukemia 1 Min Read

Ropeginterferon Alfa-2b Induces High Rates of Clinical, Hematological and Molecular Responses in PV Patients. Two – year results from the…

Two Reasons Osimertinib in 1st Line Good Toxicity Profile & Crossing Blood Brain Barrier

Acute Lymphoblastic Leukemia 1 Min Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses two reasons Osimertinib is good for first line treatment such…

Third Generation TKIs Less Diarrhea, Abdominal Issues, Rash, & Improved Life

Acute Lymphoblastic Leukemia 1 Min Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses third generation TKIs and how they cause less diarrhea, abdominal…

Profiling Standards for NSCLC Blood & Tissue Especially for Oncogenic Mutations

Acute Lymphoblastic Leukemia 2 Mins Read

Anne S. Tsao, MD of MD Anderson Cancer Center discusses profiling standards for NSCLC blood & tissue especially for oncogenic…

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