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Home » Page 30

S1500’s Completion May Alter Standard of Care for PRCC Compares 3 pool MET inhibitors to Sutent as a comparator arm

Acute Lymphoblastic Leukemia 1 Min Read

Brian M. Shuch, MD Yale School of Medicine, discusses how S1500’s Completion May Alter Standard of Care for PRCC Compares…

May Select Patients for VEGF or PD-1 Targeted Further investigation in other immunotherapies

Acute Lymphoblastic Leukemia 1 Min Read

Walter M. Stadler, MD University of Chicago, discusses how they May Select Patients for VEGF or PD-1 Targeted Further investigation…

The Importance of Statistical Analysis Plans Minimize errors, reduce amount of surprises, & diminish data mining

Acute Lymphoblastic Leukemia 1 Min Read

Maxine Sun, MD Dana-Farber Cancer Institute, discusses The Importance of Statistical Analysis Plans Minimize errors, reduce amount of surprises, &…

Role of Government in Health Care Political climate raises questions on health care as a right

Acute Lymphoblastic Leukemia 1 Min Read

Robert Uzzo, MD Fox Chase Cancer Center, discusses the Role of Government in Health Care Political climate raises questions on…

Biomarker Data From Phase II Trial Preliminary expression profiling

Acute Lymphoblastic Leukemia 1 Min Read

Walter M. Stadler, MD University of Chicago, discusses Biomarker Data From Phase II Trial Preliminary expression profiling at Kidney Cancer…

SWOG S1500 – Randomized Phase II Trial Efficacy assessment of multiple MET kinase inhibitors in metastatic PRCC

Acute Lymphoblastic Leukemia 1 Min Read

Brian M. Shuch, MD Yale School of Medicine, discusses the SWOG S1500 – Randomized Phase II Trial Efficacy assessment of…

Challenges of VEGF & Immunotherapy Combinations Resistance patterns in patients disease progression

Acute Lymphoblastic Leukemia 1 Min Read

Tian Zhang, MD Duke University Medical Center, explains the Challenges of VEGF & Immunotherapy Combinations Resistance patterns in patients disease…

Value is a Function of Outcomes and Cost Optimal care is not always related to more or less expensive care

Acute Lymphoblastic Leukemia 1 Min Read

Robert Uzzo, MD Fox Chase Center, explains how Value is a Function of Outcomes and Cost Optimal care is not…

Biomarker Data From Phase II Randomized Trial Study of Atezolizumab With or Without Bevacizumab v Sunitinib

Acute Lymphoblastic Leukemia 1 Min Read

Walter M. Stadler, MD University of Chicago, discusses Biomarker Data From Phase II Randomized Trial Study of Atezolizumab With or…

Difference Between Type 1 & 2 PRCC Although look similar on light microscopy, they have different biology

Acute Lymphoblastic Leukemia 1 Min Read

Brian M. Shuch, MD Yale School of Medicine, discusses the Difference Between Type 1 & 2 PRCC Although look similar…

The Use of Secondary Data Analysis Opportunity to produce high-impact research

Acute Lymphoblastic Leukemia 1 Min Read

Maxine Sun, MD Dana-Farber Cancer Institute, discusses The Use of Secondary Data Analysis Opportunity to produce high-impact research at Kidney…

Any association between PDL-1 expression by the tumor?

Acute Lymphoblastic Leukemia 1 Min Read

Michael B. Atkins, MD Deputy Director Professor, Oncology & Medicine Georgetown Lombardi Comprehensive Cancer Center answers if there is Any…

Gliomas in Mid-Line Locations have Distinct Make Up Defined by epigenetic and behavior

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains how Gliomas in Mid-Line Locations are Distinct in Both Genetic…

Data will not affect clinicians at the moment. Still a Phase 1 study

Acute Lymphoblastic Leukemia 1 Min Read

Michael B. Atkins, MD Deputy Director Professor, Oncology & Medicine Georgetown Lombardi Comprehensive Cancer Center answers how Data will not…

What happens to patients when treatment is stopped?

Acute Lymphoblastic Leukemia 1 Min Read

Michael B. Atkins, MD Deputy Director Professor, Oncology & Medicine Georgetown Lombardi Comprehensive Cancer Center answers What happens to patients…

Does doseage of axitnib need to be reduced?

Acute Lymphoblastic Leukemia 1 Min Read

Michael B. Atkins, MD Deputy Director Professor, Oncology & Medicine Georgetown Lombardi Comprehensive Cancer Center answers if doseage of axitnib…

How do you indentify a toxicity being related to the axitnib or the pembrolizumab?

Acute Lymphoblastic Leukemia 1 Min Read

Michael B. Atkins, MD Deputy Director Professor, Oncology & Medicine Georgetown Lombardi Comprehensive Cancer Center answers How do you indentify…

How to stay up to date as a pharmacist

Acute Lymphoblastic Leukemia 1 Min Read

Pharmacists play a valuable role in oncology practice. Here, R. Donald Harvey, PharmD, BCOP, FCCP, FHOPA, from the Winship Cancer…

The challenges of using biomarkers for immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

R. Donald Harvey, PharmD, BCOP, FCCP, FHOPA, from the Winship Cancer Institute, Atlanta, GA, gives a pharmacists perspective on the…

Pharmacist’s advice on biomarkers for immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

R. Donald Harvey, PharmD, BCOP, FCCP, FHOPA, from the Winship Cancer Institute, Atlanta, GA, discusses the importance of biomarkers in…

Thoughts on HOPA: the 2017/18 PresidentÂ’s perspective

Acute Lymphoblastic Leukemia 1 Min Read

Here, the 2017/18 President of the Hematology/Oncology Pharmacy Association (HOPA), Susannah Koontz Webb, PharmD, BCOP, FHOPA, provides an insight into…

The importance of HOPA membership: being not only a member, but an asset

Acute Lymphoblastic Leukemia 1 Min Read

Year after year, the number of healthcare professionals that join the Hematology/Oncology Pharmacy Association (HOPA) continues to increase. Speaking from…

HOPA 2018/19: whatÂ’s next?

Acute Lymphoblastic Leukemia 1 Min Read

What can be expected from the Hematology/Oncology Pharmacy Association (HOPA) in 2018/19? Here, Susannah Koontz Webb, PharmD, BCOP, FHOPA, 2017/18…

HOPA: supporting oncology pharmacy education and professional development

Acute Lymphoblastic Leukemia 1 Min Read

It was a very productive year for the 2017/18 governance of the Hematology/Oncology Pharmacy Association (HOPA). Here, Susannah Koontz Webb,…

The 2018 HOPA conference: targeting the future of oncology pharmacy

Acute Lymphoblastic Leukemia 1 Min Read

This year the Hematology/Oncology Pharmacy Association (HOPA) held its 14th Annual Conference in Denver, CO, with a record-breaking number of…

Cutaneous GVHD and the importance of the nurse

Acute Lymphoblastic Leukemia 1 Min Read

Cutaneous graft-versus-host disease (GVHD) can be a long-term complication of stem cell transplantation that requires careful management. Speaking from the…

The ECPC and the importance of patient input in clinical research

Acute Lymphoblastic Leukemia 1 Min Read

The European Cancer Patient Coalition (ECPC) is a large European cancer patients organization, comprising hundreds of patient groups from many…

The EBMT Nurses Group: supporting nurses in their careers and research

Acute Lymphoblastic Leukemia 1 Min Read

Specialist organizations, such as the European Group for Blood and Marrow Transplantation (EBMT), can provide a range of useful tools…

Sharing nursing best practice globally: from junior to expert

Acute Lymphoblastic Leukemia 1 Min Read

The European Group for Blood and Marrow Transplantation Nurses Group (EBMT NG) is committed to improving medical education worldwide, to…

A rich digital resource for hemonc nurses: the EBMT NG website

Acute Lymphoblastic Leukemia 1 Min Read

The European Group for Blood and Marrow Transplantation Nurses Group (EBMT NG) is a rich resource for nurses and allied…

Sharing of knowledge and practice improvement at EBMT

Acute Lymphoblastic Leukemia 1 Min Read

The European Group for Blood and Marrow Transplantation (EBMT) held its 44th Annual Meeting in 2018, with delegates once again…

Veno-occlusive disease e-learning for nurses

Acute Lymphoblastic Leukemia 1 Min Read

Veno-occlusive disease (VOD) is a serious complication that can occur following stem cell transplantation, for which the appropriate management is…

The EBMT NG awards: recognizing and sharing the work of nurses

Acute Lymphoblastic Leukemia 1 Min Read

The European Group for Blood and Marrow Transplantation Nurses Group (EBMT NG), founded in 1985, is a well-established coalition that…

EBMT and the EBMT Nurses Group: improving patient care

Acute Lymphoblastic Leukemia 1 Min Read

The European Group for Blood and Marrow Transplantation (EBMT) is committed to developing and advancing the care of patients. In…

Safety and efficacy of axitinib in combination with pembrolizumab in patients with advanced renal cell cancer

Acute Lymphoblastic Leukemia 1 Min Read

Michael B. Atkins, MD Deputy Director Professor, Oncology & Medicine Georgetown Lombardi Comprehensive Cancer Center discusses the efficacy of axitinib…

ADD – Best options for early relapse after undergoing VRd therapy with stem cell transplant?

Acute Lymphoblastic Leukemia 1 Min Read

In this video, Dr. Brian G.M. Durie explains that second transplant and certain novel therapies may work well for early…

ADD-What impact do Revlimid® (lenalidomide) and Pomalyst® (pomalidomide) have on the bone marrow?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Brian G.M. Durie explains that even though Revlimid and Pomalyst may reduce white blood cell counts,…

ADD-What supplements, if any, should a myeloma patient take?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie explains that supplements might have side effects or might interfere with medications…

Reckamp Immunotherapy for Previously Treated Patients with NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Karen Reckamp, MD, MS, Co-Director of the Lung Cancer and Thoracic Oncology Program, Medical Director – Clinical Research Operations,…

Reckamp the Role of Angiogenesis in Previously Treated NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Karen Reckamp, MD, MS, Co-Director of the Lung Cancer and Thoracic Oncology Program, Medical Director – Clinical Research Operations,…

RAEZ PDL1como biomarcador para segundo tratamiento [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Luis Raez, MD FACP FCCP, Chief of Hematology/Oncology and Medical Director at Memorial Cancer Institute, and Clinical Associate Professor…

Spanish Lung Cancer Video Library_ PDL1 como biomarcador para primer tratamiento [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Luis Raez, MD FACP FCCP, Chief of Hematology/Oncology and Medical Director at Memorial Cancer Institute, and Clinical Associate Professor…

Pennell New Options in Acquired Resistance for ALK Positive Non-small Cell Lung Cancer (NSCLC) [720p]

Acute Lymphoblastic Leukemia 1 Min Read

We are pleased to have Nathan Pennell, MD, PhD, Director of Lung Cancer Medical Oncology at the Cleveland Clinic Taussig…

Pennell The Role for Immunotherapy in Patients with a Driver Mutation [720p]

Acute Lymphoblastic Leukemia 1 Min Read

We are pleased to have Nathan Pennell, MD, PhD, Director of Lung Cancer Medical Oncology at the Cleveland Clinic Taussig…

Pennell Liquid Biopsies for Broad Genomic Testing in Lung Cancer [720p]

Acute Lymphoblastic Leukemia 1 Min Read

We are pleased to have Nathan Pennell, MD, PhD, Director of Lung Cancer Medical Oncology at the Cleveland Clinic Taussig…

Pennell Liquid Biopsies for EGFR T790M NonSmall Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Nate Pennell, Director of Lung Cancer Medical Oncology at Cleveland Clinic Taussig Cancer Center shares 2017 updates for our…

First Line EGFR Based Therapy For Advanced Squamous Non Small Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

http://cancerGRACE.org/

What Is the Optimal Follow-up for Patients After Resection of an Early Stage NSCLC_ [720p]

Acute Lymphoblastic Leukemia 1 Min Read

http://cancerGRACE.org/

Should Immunotherapy Stop in Responding Patients After a Fixed Duration of Treatment_ [720p]

Acute Lymphoblastic Leukemia 1 Min Read

http://cancerGRACE.org/

The Changing Landscape of First Line Treatment for EGFR Mutation-Positive NSCLC. [720p]

Acute Lymphoblastic Leukemia 1 Min Read

http://cancerGRACE.org/

The Changing Standard of Care for Stage 3 Non-Small Cell Lung Cancer (NSCLC) [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West offers discussions for 2017 regarding the changing standard of care for stage 3 non-small cell lung cancer…

Is There A Role For PD L1 Testing After First Line Treatment For Advanced Non Small Cell Lung Cancer [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

First Line EGFR Based Therapy For Advanced Squamous Non Small Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

Is There An Optimal Chemo Regimen For Squamous Non Small Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

What is the role for PD L1 testing for adv.NSCLC in initial diagnosis [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

Lung Cancer Video Library – PDL1 As A Biomarker For First Line [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. West discusses exciting new advances in NSCLC – PDL1 as a Biomarker for First Line.

Timing Of Discussion Of Maintenance Therapy In First Line Treatment for Lung Cancer [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

PDL1 As A Biomarker For Second Line [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

Novel Therapies In Small Cell Lung Cancer (SCLC)_ Lurbinectedin [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

BRAF V600E As A Target In Advanced Non Small Cell Lung Cancer [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

Emerging Molecular Targets For Advanced Non Small Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

Molecular Testing At Initial Diagnosis Of Advanced Non Small Cell Lung Cancer [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library. http://cancerGRACE.org/

Continuing Immunotherapy Beyond Progression. In Which Patients Is This Appropriate [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Lung Cancer Video Library http://cancerGRACE.org/

Lung Cancer Risk Factors [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jared Weiss, UNC Lineberger Comprehensive Cancer Center, discusses the demographics and epidemiology of lung cancer.

Lung Cancer Demographics_Epidemiology [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jared Weiss, UNC Lineberger Comprehensive Cancer Center, discusses the demographics and epidemiology of lung cancer.

Liquid Biopsies for Broad Next Generation Sequencing Testing [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

Liquid Biopsies for EGFR [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

Role for Immunotherapy for Patients with Driver Mutations [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

Multiple Immunotherapy Agents [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

Evolving Options in First Line Treatment of ALK Positive Non Small Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

First Line Immunotherapy for Advanced Non Small Cell Lung Cancer NSCLC [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

First Line Combinations, Immunotherapy with Chemo [720p]

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Dr. Luis E. Raez, MD, FACP, FCCP Chief of Hematology/Oncology and Medical Director of Memorial Cancer Institute (Miami,…

Will Work with Distant Patients to Get Them on ONC201 Trial

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains How they Will Work with Distant Patients to Get Them…

NYU is 1st Actively Enrolling Site for ONC201 in Adults With Recurrent H3 K27M High-grade Glioma Trial

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains How NYU is 1st Actively Enrolling Site for ONC201 in…

Patients Must Have H3 K27M Tumor Mutation for Clinical Trial with ONC201

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains How Patients Must Have H3 K27M Tumor Mutation for Clinical…

ONC201 is Taken Orally with Minimal Side Effects

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains How ONC201 is Taken Orally with Minimal Side Effects. Clinical…

Patients Must Have Progressive Disease after 1st Line of Therapy to Enroll in ONC201 Trial

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains How Patients Must Have Progressive Disease after 1st Line of…

Phase 2 Clinical Trial of ONC201 in Patients with Glioma that has H3 K27M Mutation 

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center Explains Phase 2 Clinical Trial of ONC201 in Patients with Glioma…

K27M Mutations are Rare within Gliomas, an Already Rare Cancer Type

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center explains how K27M Mutations are Rare within Gliomas, an Already Rare…

ONC201 has Selectivity Anti-Cancer Properties and is a Dopamine Receptor D2 Antagonist 

Acute Lymphoblastic Leukemia 1 Min Read

Andrew Chi, MD, PhD at NYU Langone Medical Center explains how ONC201 has Selectivity Anti-Cancer Properties and is a Dopamine…

Tailoring Therapy to Older Patients with Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Aziz Nazha, MD. Acute myeloid leukemia (AML) is generally a hematologic malignancy of older adults, with approximately 60%…

Novel Treatment Combinations in Development for AML: The Role of Hypomethylating Agents

Acute Lymphoblastic Leukemia 1 Min Read

Presented by Ehab Atallah, MD. There is a significant unmet need in existing treatment paradigms for patients with acute myeloid…

Checkpoint inhibitors for lung cancer: combating resistance

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy has the potential to provide long-term benefits to certain lung cancer patients; however, certain patients may not respond, while…

The importance of supporting carers of lung cancer patients: an unmet need

Acute Lymphoblastic Leukemia 1 Min Read

Informal carers play an essential role in the care of many lung cancer patients. Here, Morag Farquhar, PhD, of the…

Breathlessness in lung cancer: increasing awareness

Acute Lymphoblastic Leukemia 1 Min Read

Breathlessness is a frightening and disabling symptom of lung cancer; therefore, it is vital that patients, carers, family and healthcare…

Educational intervention for carers of lung cancer patients: learning about breathlessness

Acute Lymphoblastic Leukemia 1 Min Read

Breathlessness is a scary symptom for lung cancer patients and their family, who often act as informal carers. Speaking from…

Patient advocacy: an essential role

Acute Lymphoblastic Leukemia 1 Min Read

Patient advocacy, by individuals and organizations, serves an imperative role in healthcare, giving a voice to those who are most…

Patient support NETworks: the NET Patient Foundation

Acute Lymphoblastic Leukemia 1 Min Read

The neuroendocrine tumor (NET) Patient Foundation is a valuable resource for patients with NETs, as well as their carers. Here,…

CAR T-cell therapy for lung cancer?

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cells are an exciting therapeutic area, which although promising are still in the early stages of development for solid…

Lung cancer immuno-oncology clinical trial combinations: inhibiting IDO

Acute Lymphoblastic Leukemia 1 Min Read

There are numerous ongoing and planned clinical trials investigating immuno-oncology (IO) agents for lung cancer, particularly in combination with other…

Rapid access to lung cancer care in the UK: the NOLCP

Acute Lymphoblastic Leukemia 1 Min Read

For lung cancer, early diagnosis and staging is crucial to survival. However, the length of the lung cancer pathway differs…

Mesothelioma surgical trial updates in the UK: MARS2 and MesoTRAP

Acute Lymphoblastic Leukemia 1 Min Read

Exciting clinical trial updates were presented at the British Thoracic Oncology Group (BTOG) Annual Conference 2018, held in Dublin, Ireland.…

The future of lung cancer management: an unmet need in the immuno-oncology era

Acute Lymphoblastic Leukemia 1 Min Read

In the coming era of lung cancer management, where the use of both targeted agents and new immunotherapies seems extremely…

Immuno-oncology focus: questions to be answered

Acute Lymphoblastic Leukemia 1 Min Read

A key subject on everyones mind at the British Thoracic Oncology Group (BTOG) Annual Conference 2018, held in Dublin, Ireland,…

Biostatistics: can we produce more valid results from trials?

Acute Lymphoblastic Leukemia 1 Min Read

The British Thoracic Oncology Group (BTOG) Annual Conference 2018, held in Dublin, Ireland, hosted sessions covering a diverse range of…

ctDNA signatures to detect lung cancer

Acute Lymphoblastic Leukemia 1 Min Read

This is an exciting time for research into the early diagnosis of lung cancer, with a number of promising options…

Exhaled breath signatures for lung cancer detection: the LuCID study

Acute Lymphoblastic Leukemia 1 Min Read

There is a growing need to improve the early diagnosis of lung cancer; non-invasive, quick and accessible assays would greatly…

Identifying non-invasive biomarker assays for lung cancer: what is an appropriate control group?

Acute Lymphoblastic Leukemia 1 Min Read

A non-invasive biomarker assay to detect lung cancer would be ideal; avoiding needless biopsies and providing another step of diagnostic…

Lung cancer screening challenge: how do we prevent unnecessary biopsies?

Acute Lymphoblastic Leukemia 1 Min Read

One issue with lung cancer screening is that nodules, which may or may not be malignant, can be detected, leading…

Future challenges in lung cancer: long-term control and trial selectivity

Acute Lymphoblastic Leukemia 1 Min Read

With rapid advancements in the management of lung cancer, new questions and challenges undoubtedly arise. Here, James Spicer, PhD, FRCP,…

Lung cancer immunotherapy: the need for predictive biomarkers

Acute Lymphoblastic Leukemia 1 Min Read

As explained here by James Spicer, PhD, FRCP, of Guy’s and St Thomas’ NHS Foundation Trust, London, UK, the field…

Emerging targets and drug developments in NSCLC

Acute Lymphoblastic Leukemia 1 Min Read

As our understanding of the different oncogenes that serve a role in the pathogenesis of lung cancer increases, so does…

Lung cancer screening in the UK: yes or no?

Acute Lymphoblastic Leukemia 1 Min Read

Lung cancer screening is an exciting and greatly debated topic in the UK; on one hand it could greatly improve…

Improving lung cancer care in the UK: what changes can be made?

Acute Lymphoblastic Leukemia 1 Min Read

Lung cancer management in the UK is on the pinnacle of great change, with the current implementation of the National…

National Optimal Lung Cancer Pathway (NOLCP): an introduction

Acute Lymphoblastic Leukemia 1 Min Read

The National Optimal Lung Cancer Pathway (NOLCP), a hugely accelerated new lung cancer care pathway in the UK, was a…

The recording and referral of smokers in the UK: an area for improvement

Acute Lymphoblastic Leukemia 1 Min Read

Tobacco use is a major determinant of lung cancer risk; therefore, it is vital that a patients smoking status and…

Implementing the National Optimal Lung Cancer Pathway in the UK: all hospitals vs. diagnostic centers?

Acute Lymphoblastic Leukemia 1 Min Read

The National Optimal Lung Cancer Pathway (NOLCP), a streamlined care pathway to improve the speed of lung cancer diagnosis, staging…

How can we continue the success of checkpoint inhibitors for bladder cancer treatment?

Acute Lymphoblastic Leukemia 1 Min Read

The past several years have been extremely exciting in the field of bladder cancer, with checkpoint inhibitors emerging as efficacious…

A golden age for bladder cancer publications

Acute Lymphoblastic Leukemia 1 Min Read

The 2018 Genitourinary Cancers Symposium, held in San Francisco, CA, hosted an exciting Best of Journals session, highlighting key research…

Unmet needs in bladder cancer in the immunotherapy era

Acute Lymphoblastic Leukemia 1 Min Read

Despite there now being a variety of promising immunotherapies for bladder cancer, a large proportion of patients dont respond to…

Dr. Kesari on Neuro-Oncology Some patients do well if given treatments in neoadjuvant

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, shares Dr. Kesari on Neuro-Oncology Some patients do well if given treatments in neoadjuvantat the 2018 Oncology…

Dr. Fakih’s Talk on Colorectal Cancer Microsatellite instability is an approved biomarker

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, shares Dr. Fakih’s Talk on Colorectal Cancer Microsatellite instability is an approved biomarker at the 2018 Oncology…

Dr. Hurvitzs Study on Breast Cancer Using Tumor-Infiltrating Lymphocytes as a biomarker

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, shares Dr. Hurvitzs Study on Breast Cancer Using Tumor-Infiltrating Lymphocytes as a biomarker at the 2018 Oncology…

Dr. Reckcamp Overview on Lung Cancer Combine established Immunotherapy w new therapies

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, shares Dr. Reckcamp Overview on Lung Cancer Combine established Immunotherapy with new therapies at the 2018 Oncology…

Dr. Hamid On Metastatic Melanoma IDO Inhibitors can help overcome resistance

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, shares Dr. Hamid On Metastatic Melanoma IDO Inhibitors can help overcome resistance at the 2018 Oncology Summit…

Dr. Powells Study On RCC & Bladder Tumors Augment treatment responses with good safety signals

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, shares Dr. Powells Study On RCC & Bladder Tumors Augment treatment responses with good safety signals at…

MOASC Overview – Highlights from Presentations A number of speakers talk across different tumor types

Acute Lymphoblastic Leukemia 1 Min Read

Ashkan Lashkari, MD, gives a MOASC Overview – Highlights from Presentations A number of speakers talk across different tumor types…

Looking Forward to Mature Data on Glioblastoma Updates from Antibody-based trials

Acute Lymphoblastic Leukemia 1 Min Read

Santosh Kesari, MD, explains Looking Forward to Mature Data on Glioblastoma Updates from Antibody-based trials at the 2018 Oncology Summit…

Patients May Benefit from Molecular Profiling of Tumor BRAF, PI3K, etc, would benefit from available drugs

Acute Lymphoblastic Leukemia 1 Min Read

Santosh Kesari, MD, explains Patients May Benefit from Molecular Profiling of Tumor BRAF, PI3K, etc, would benefit from available drugs…

Immunotherapy Can have Activity in the Brain Do better at managing toxicities

Acute Lymphoblastic Leukemia 1 Min Read

Santosh Kesari, MD, discusses how Immunotherapy Can have Activity in the Brain Do better at managing toxicities at the 2018…

Immunotherapy in Glioma Study in the neoadjuvant setting

Acute Lymphoblastic Leukemia 1 Min Read

Santosh Kesari, MD, Immunotherapy in Glioma Study in the neoadjuvant setting at the 2018 Oncology Summit in Huntington Beach, CA…

POUT trial: a new standard of care for upper tract urothelial carcinoma

Acute Lymphoblastic Leukemia 1 Min Read

There was exciting news in the field of bladder cancer treatment at the 2018 Genitourinary Cancers Symposium, held in San…

APF in prostate cancer patients following radical prostatectomy: what happens next?

Acute Lymphoblastic Leukemia 1 Min Read

Whether or not patients with prostate cancer with adverse pathological features (APF) following radical prostatectomy should be offered radiotherapy immediately…

Case-based debate: is there evidence for local treatment in oligometastatic prostate cancer?

Acute Lymphoblastic Leukemia 1 Min Read

Patients with oligometastatic prostate cancer can be identified using highly advanced detection tools, such as positron emission tomography (PET) and…

Treatment options for patients with bladder cancer, is bladder removal always necessary?

Acute Lymphoblastic Leukemia 1 Min Read

Bladder preservation remains a viable option for certain patients with bladder cancer; with previous studies showing that patients up to…

Addressing the issues faced in the ProtecT trial for patients with localized prostate cancer

Acute Lymphoblastic Leukemia 1 Min Read

The ProtecT trial (NCT02044172) was a study conducted between 1999 and 2009 that compared active monitoring, radical prostatectomy and radiotherapy…

10-year follow-up: the most effective treatment to ProtecT patients with localized prostate cancer?

Acute Lymphoblastic Leukemia 1 Min Read

An interesting update on the ProtecT trial (NCT02044172) was given by Freddie Hamdy, MBChB, LRCSPEd, LRCSEd, LRCPSGlasg, FRCSEd, MD, FRCSEd(Urol),…

PROs of the ProtecT trial: is using data provided by patients a good tool for counselling?

Acute Lymphoblastic Leukemia 1 Min Read

Patient reported outcomes (PROs) are reports that can provide insightful information from patients, including how they feel about their condition…

ProtecT trial: a battle between three treatments for patients with localized prostate cancer

Acute Lymphoblastic Leukemia 1 Min Read

Active monitoring, radical prostatectomy or radiotherapy? For men with clinically localized prostate cancer, which intervention has a disease-specific mortality advantage?…

NCRI and UKONS: a discussion on clinical trial participation

Acute Lymphoblastic Leukemia 1 Min Read

The nurses role in talking about trials was an interesting session run by the UK Oncology Nursing Society (UKONS) symposium…

NCRI welcomes UKONS: experience at NCRI 2017

Acute Lymphoblastic Leukemia 1 Min Read

The National Cancer Research Institute (NCRI) invited the UK Oncology Nursing Society (UKONS) to host a session at the 2017…

“Clinical trials?”: breaking the ice between young cancer patients and clinicians

Acute Lymphoblastic Leukemia 1 Min Read

Discussing clinical trials with young cancer patients can be tricky; are there certain strategies that can be implemented to help…

UKONS at NCRI: how can trial access for young cancer patients be improved by nurses?

Acute Lymphoblastic Leukemia 1 Min Read

It has been found that the Clinical Nurse Specialist has a central role working alongside research nurses and doctors to…

Next steps in VTE treatment: will oral edoxoban replace the current standard of care?

Acute Lymphoblastic Leukemia 1 Min Read

There was exciting news at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA, with…

Harnessing T-cells in acute leukemia and an anti-CD33/CD3 BiTE antibody

Acute Lymphoblastic Leukemia 1 Min Read

To date, stem cell transplantation has been the best curative treatment method for acute leukemia, for which T-cells are the…

T-cell engaging antibodies: novel combinations to overcome resistance

Acute Lymphoblastic Leukemia 1 Min Read

Acute leukemias can exhibit resistance to T-cell engaging antibodies through immune evasion, via both innate and adaptive mechanisms. In this…

Target antigens for T-cell engager therapies in ALL and AML

Acute Lymphoblastic Leukemia 1 Min Read

T-cell engaging antibodies are more straightforward to deisgn and use in acute lymphoblastic leukemia (ALL) compared with acute myeloid leukemia…

Dr. Thom George discusses colorectal cancer

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Thomas George, Medical Director of GI Oncology Program at the University of Florida and a NSABP Principal Investigator discusses…

The Hokusai VTE-Cancer Study: objectives and design

Acute Lymphoblastic Leukemia 1 Min Read

What were the objectives of the Hokusai venous thromboembolism (VTE)-Cancer Study? In this interview, Harry Buller, MD, PhD, of the…

The Hokusai VTE-Cancer Study: the importance of improving VTE treatment

Acute Lymphoblastic Leukemia 1 Min Read

Venous thromboembolism (VTE) remains a major risk for patients with cancer. The current standard of care for VTE includes subcutaneously…

The diagnosis of early T-cell precursor (ETP) ALL

Acute Lymphoblastic Leukemia 1 Min Read

Our knowledge of early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is advancing, as highlighted by an excellent talk on the…

Reckamp Immunotherapy for Previously Treated Patients with NSCLC

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Karen Reckamp, MD, MS, Co-Director of the Lung Cancer and Thoracic Oncology Program, Medical Director – Clinical Research Operations,…

Molecular subtypes of ALL: coming to a consensus

Acute Lymphoblastic Leukemia 1 Min Read

We are continually learning new facts about the molecular basis of acute lymphoblastic leukemia (ALL) and how it is evolving.…

Status of the ZUMA-3 trial of CAR T-cell product KTE-C19 for R/R ALL

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cells for acute lymphoblastic leukemia (ALL) treatment are promising, with a number of different agents in development. Here, Bijal…

We know that MRD is relevant, what next?

Acute Lymphoblastic Leukemia 1 Min Read

It is now widely agreed that minimal residual disease (MRD) is a clinically relevant measure, so how can we now…

How should we utilizing molecular data to improve ALL treatment?

Acute Lymphoblastic Leukemia 1 Min Read

Certain molecular lesions are inherently targetable in acute lymphoblastic leukemia (ALL); patients with these changes should be given access to…

The role of MRD in ALL: what defines a complete response?

Acute Lymphoblastic Leukemia 1 Min Read

Now that our techniques to measure minimal residual disease (MRD) are highlighly sensitive, the utility of MRD to guide and…

Identify Who Can Take Immunotherapy in the First-Line The durability of responses would be much better

Acute Lymphoblastic Leukemia 1 Min Read

Marwan Fakih, MD, explains Identify Who Can Take Immunotherapy in the First-Line The durability of responses would be much better…

Presented Data has Affected Day-to-Day Practice Has already been affecting MSI-High patients

Acute Lymphoblastic Leukemia 1 Min Read

Marwan Fakih, MD, shares Presented Data has Affected Day-to-Day Practice Has already been affecting MSI-High patients at the 2018 Oncology…

Comparative Studies in the Neoadjuvant setting All presentations have been single agent studies

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, shares Comparative Studies in the Neoadjuvant setting All…

Disappointing Data for Patients without MSI Great responses to checkpoint inhibitors

Acute Lymphoblastic Leukemia 1 Min Read

Marwan Fakih, MD, explains Disappointing Data for Patients without MSI Great responses to checkpoint inhibitors at the 2018 Oncology Summit…

Trials Evaluating Immunotherapies for Breast Cancer Either as single agent or with chemotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, examines Trials Evaluating Immunotherapies for Breast Cancer Either…

Lack of Randomized Data to Compare Drugs Nivolumab + Ipilimumab showed high response rate Randomized Data to Compare 1 Drug to Another

Acute Lymphoblastic Leukemia 1 Min Read

Marwan Fakih, MD, explains Lack of Randomized Data to Compare Drugs Nivolumab + Ipilimumab showed high response rate Randomized Data…

Not Using Anthracycline-based Therapies Patients accumulate loss of heterozygosity & MSI

Acute Lymphoblastic Leukemia 1 Min Read

ara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, explains Not Using Anthracycline-based Therapies Patients accumulate loss…

Microsatellite Instability in Colorectal Cancer PD-1 Inhibitors have a significant response rate

Acute Lymphoblastic Leukemia 1 Min Read

Marwan Fakih, MD, explains Microsatellite Instability in Colorectal Cancer PD-1 Inhibitors have a significant response rate at the 2018 Oncology…

Immune Therapy Toxicities Related to Breast Cancer Thyroid and adrenal insufficiency

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, examines Immune Therapy Toxicities Related to Breast Cancer…

TAPUR Study – FDA approved therapies Targeted therapies such as BRAF, CDK2NA, etc.

Acute Lymphoblastic Leukemia 1 Min Read

Omid Hamid MD Chief, Translational Research/Immuno-Oncology Director shares, TAPUR Study – FDA approved therapies Targeted therapies such as BRAF, CDK2NA,…

Immunotherapy Not Recommended Outside Trials Pembrolizumab for Microsatellite Instability or MMR

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, shares Immunotherapy Not Recommended Outside Trials Pembrolizumab for…

Metastases Treated with Anti-CTLA-4 & Anti-PD-1 Shows immunotherapies to affect brain metastases

Acute Lymphoblastic Leukemia 1 Min Read

Omid Hamid MD Chief, Translational Research/Immuno-Oncology Director explains, Metastases Treated with Anti-CTLA-4 & Anti-PD-1 Shows immunotherapies to affect brain metastases…

Studies in Neoadjuvant, Curative, & Metastatic Settings Ongoing studies to evaluate immune therapy usage

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, examines Studies in Neoadjuvant, Curative, & Metastatic Settings…

Create Roadmap for Therapies for Solid Tumors Encouraging data shows multiple options exist

Acute Lymphoblastic Leukemia 1 Min Read

Omid Hamid MD Chief, Translational Research/Immuno-Oncology Director explains, Creating Roadmap for Therapies for Solid Tumors Encouraging data shows multiple options…

Immune-Targeted Therapy in Breast Cancer Immune System Important for Long-Term Outcome

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, examines Immune-Targeted Therapy in Breast Cancer Immune System…

238 Trial – Nivolumab as Standard for Melanoma Therapeutics Available for Relapsed Immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Omid Hamid MD Chief, Translational Research/Immuno-Oncology Director explains, 238 Trial – Nivolumab as Standard for Melanoma Therapeutics Available for Relapsed…

Future frontiers in AML: the five key therapy pillars & the future of trials

Acute Lymphoblastic Leukemia 1 Min Read

Acute myeloid leukemia (AML) is experiencing a therapy boom, with increasing numbers of novel treatments being approved and more in…

Lifting limits: liposomal delivery of chemotherapy for secondary AML with CPX-351

Acute Lymphoblastic Leukemia 1 Min Read

Elderly patients with secondary acute myeloid leukemia (AML) typically had poor outcomes following standard chemotherapy treatment. However, this changed in…

Liposomal chemotherapy CPX-351: safety profile

Acute Lymphoblastic Leukemia 1 Min Read

CPX-351, a combination of cytarabine (ara-C) and daunorubicin within a liposomal delivery system, was approved in August 2017 for two…

What are the next steps for liposomal chemotherapy delivery and CPX-351?

Acute Lymphoblastic Leukemia 1 Min Read

The liposomal delivery of chemotherapy is a promising therapeutic area, which was highlighted by the approval of CPX-351 for two…

Making an IMPACT in ALL therapy: how can cure rates be improved?

Acute Lymphoblastic Leukemia 1 Min Read

Hear about exciting advancements in acute lymphocytic leukemia (ALL) with Prof. David Marks, MBBS, PhD, FRACP, FRCPath, of University Hospitals…

Palliative care Outcome Scale (POS): a new tool to assess the use of palliative care in cancer patients

Acute Lymphoblastic Leukemia 1 Min Read

In this exciting interview, Irene Higginson, OBE, BMBS, PhD, FMedSci, FRCP, of Kings College London, London, UK, introduces the palliative…

Nelarabine as first-line treatment for T-cell ALL: facing the problem up-front

Acute Lymphoblastic Leukemia 1 Min Read

Nelarabine has shown to be effective in treating relapsed/refractory T-cell acute lymphocytic leukemia (T-ALL) in children and adults; however, there…

Rituximab vs. standard chemotherapy: which treatment benefits B-cell ALL patients more?

Acute Lymphoblastic Leukemia 1 Min Read

Can patients with B-cell acute lymphocytic leukemia (ALL) benefit more from using rituximab as part of their treatment compared to…

When should palliative care be offered to cancer patients?

Acute Lymphoblastic Leukemia 1 Min Read

In recent years, there has been a lot of debate surrounding how palliative care should be integrated into the cancer…

How can palliative care be integrated into the care of cancer patients earlier?

Acute Lymphoblastic Leukemia 1 Min Read

Palliative care can offer patients with progressive cancer a better quality of life, but how can this type of care…

When Will Tumor Mutational Burden be a Standard Trials analyzing responses, not FDA-approved yet

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations shares When Will Tumor Mutational Burden be a Standard Trials analyzing…

Stage III Lung Cancer Receptible vs. Unreceptible

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations shares Stage III Lung Cancer Receptible vs. Unreceptible at the 2018…

Refine Patient Subsets & Define Combinations

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations explains Refine Patient Subsets & Define Combinations at the 2018 Oncology…

New Lung Cancer Data Already in the Forefront Upcoming meetings will help define best use of data

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations explains New Lung Cancer Data Already in the Forefront Upcoming meetings…

First-Line Therapy for Squamous Cell Lung Cancer Multiple Positive Trials from Various Combinations

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations shares First-Line Therapy for Squamous Cell Lung Cancer Multiple Positive Trials…

Continue to Refine Understanding of Biomarkers Find the right combinations with least toxicity

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations shares the Continuation to Refine Understanding of Biomarkers and Find the…

Immunotherapy in Melanoma: WhatÂ’s up next?

Acute Lymphoblastic Leukemia 1 Min Read

Omid Hamid MD Chief, Translational Research/Immuno-Oncology Director presents, Immunotherapy in Melanoma at the 2018 Oncology Summit in Huntington Beach, CA…

ADD – What are the options for a myeloma patient who has relapsed on a two-drug combination?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie advises that patients discuss with their doctors the many aspects of various…

ADD – What should patients do if their doctor is unsure if they have smoldering or active myeloma?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie emphasizes the importance of correctly diagnosing and staging myeloma before beginning treatment…

Several Elements Factor into Rising Drug Costs Time, development, and innovation adds value to drug costs

Acute Lymphoblastic Leukemia 1 Min Read

Robert Uzzo, MD Fox Chase Cancer Center, discusses Several Elements Factor into Rising Drug Costs Time, development, and innovation adds…

ADD – Should patients with light chain myeloma be more wary of disease outcomes than those with other types of myeloma?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie explains that the underlying biology of light chain myeloma is very similar…

ADD – How do the two approaches to treating high-risk smoldering multiple myeloma (HRSMM) patients differ?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie compares two trials that treat high-risk smoldering multiple myeloma the CESAR trial…

ADD – Can you explain the results of the IFM 2009 trial?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie explains the somewhat confusing results of the IFM 2009 trial. BOTTOM LINE:…

ADD – What is MRD, or Minimal Residual Disease?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie defines minimal residual disease (MRD) and explains how MRD-testing can be used…

ADD – Should a myeloma patient take supplements such as selenium?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie explains why myeloma patients should discuss the use of supplements with their…

ADD – Should the cost of Revlimid (lenalidomide) be reduced?

Acute Lymphoblastic Leukemia 1 Min Read

In this weeks video, Dr. Brian G.M. Durie addresses why the cost of patented drugs, such as Revlimid, have not…

Immunotherapy in Neuro-Oncology

Acute Lymphoblastic Leukemia 1 Min Read

Santosh Kesari, MD, PhD, Chair, Department of Neurosciences and Neurotherapeutics, John Wayne Cancer Institute & Pacific Neuroscience Institute examines Immunotherapy…

The Role of Immunotherapy in Breast Cancer

Acute Lymphoblastic Leukemia 1 Min Read

Sara A Hurvitz, MD, FACP Associate Professor of Medicine Director, Breast Oncology, examines The Role of Immunotherapy in Breast Cancer…

Investigating the Tumor Immune Response to Optimize Treatment in Colorectal Cancer

Acute Lymphoblastic Leukemia 1 Min Read

Marwan Fakih, MD, explains Investigating the Tumor Immune Response to Optimize Treatment in Colorectal Cancer at the 2018 Oncology Summit…

Harnessing the Power of Immunotherapy—Lung Cancer

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations provides an in-depth look at Harnessing the Power of ImmunotherapyLung Cancer…

Lung Cancer Immunotherapy Advances PDL-1 and Tumor Mutational Burden

Acute Lymphoblastic Leukemia 1 Min Read

Karen Reckamp, MD, MS Medical Director, Clinical Research Operations shares Lung Cancer Immunotherapy Advances PDL-1 and Tumor Mutational Burden at…

Papillary Kidney Cancer SWOG 1500 – Multiple MET Kinase Inhibitors

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Nivolumab + Ipilimumab Front Line bevacizumab atezolizumab

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Cabozantinib + Atezolizumab looks promising in kidney cancer

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Bladder Cancer Immunotherapy or Chemo Immunotherapy 25-50 Chemo 50-75

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Adjuvant Therapy in Kidney Cancer steering toward immunotherapies in the future

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Adjuvant Immunotherapy Trial may be preferable to Adjuvant therapy in Kidney Cancer

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Advances in Immunotherapy for GU Cancers: Focus on Renal Cell Carcinoma

Acute Lymphoblastic Leukemia 1 Min Read

Sumanta (Monty) Kumar Pal, M.D. Associate Clinical Professor, Department of Medical Oncology & Therapeutics Research Co-director, Kidney Cancer Program, Medical…

Immune checkpoint inhibitors for AML: mechanism, rationale & using azacitidine to boost response

Acute Lymphoblastic Leukemia 1 Min Read

Immune checkpoint inhibitors are a promising area of therapy, with our understanding of their mechanism of action and the ways…

Checkpoint inhibitors: parallel management of the disease and immune-related toxicities

Acute Lymphoblastic Leukemia 1 Min Read

As our knowledge of immunotherapy increases, so has our understanding of its side effects. In this interview, Naval Daver, MD,…

Update on checkpoint inhibitor therapy for AML: salvage, frontline & azacitidine combination

Acute Lymphoblastic Leukemia 1 Min Read

The use of immune checkpoint inhibitor therapy for acute myeloid leukemia (AML) has progressed drastically over the past several years.…

Targeting sonic hedgehog signaling in AML

Acute Lymphoblastic Leukemia 1 Min Read

Aberrations in sonic hedgehog (shh) signaling are known to be associated with certain types of cancer, including acute myeloid leukemia…

Is low-dose cytarabine being overlooked in combination therapies for elderly AML?

Acute Lymphoblastic Leukemia 1 Min Read

Low-dose cytarabine (ara-C) is not generally perceived as a good therapy for AML, particularly in the US, whereas hypomethylating agents…

Smoothening the spines: hedgehog signaling inhibitor glasdegib combinations for AML

Acute Lymphoblastic Leukemia 1 Min Read

Therapeutically targeting the sonic hedgehog (shh) signaling pathway for the treatment of acute myeloid leukemia (AML) is an exciting area,…

MOASC Oncology Summit Kick Off

Acute Lymphoblastic Leukemia 1 Min Read

MOASC Oncology Summit Kick Off March 3rd, 2018. Dr. Warren H. Fong, MD MOASC President kicks off the 2018 Oncology…

iwAL 2018 day 2 discussion: novel approaches and targeted therapies in AML

Acute Lymphoblastic Leukemia 1 Min Read

A plethora of novel treatments for acute myeloid leukemia (AML) are emerging, providing an increasing choice of therapies and bringing…

Acute leukemias discussion: what does genomics and epigenomics tell us about patient management?

Acute Lymphoblastic Leukemia 1 Min Read

A stimulating session on the implications of genomic data for the management of acute myeloid leukemia (AML) and acute lymphoblastic…

Genomics and acute leukemia management: artificial intelligence, deep learning & pre-leukemic clones

Acute Lymphoblastic Leukemia 1 Min Read

An interesting session on the impact of genomic data on the management of acute myeloid leukemia (AML) and acute lymphoblastic…

CONTI-PV: a 2-year follow-up of interferon product AOP2014

Acute Lymphoblastic Leukemia 1 Min Read

Interesting results were produced in the PROUD-PV Study (NCT01949805), which compared the treatment of ropeginterferon alpha-2b with hydroxyurea in patients…

A RESPONSE to ruxolitinib: update on 4-year trial follow-up

Acute Lymphoblastic Leukemia 1 Min Read

An exciting update on the 4-year follow-up of the RESPONSE Trial (NCT01243944) was given by Jean-Jacques Kiladjian, MD, PhD, of…

What can be learnt about using interferon in patients with myelofibrosis?

Acute Lymphoblastic Leukemia 1 Min Read

Treating patients who suffer from myelofibrosis with interferon used to be considered inappropriate due to the drug being poorly tolerated.…

Recent subtypes of ALL: Ph-like ALL and ETP ALL

Acute Lymphoblastic Leukemia 1 Min Read

Recent insights from the genomic analysis of acute lymphoblastic leukemia (ALL) were presented at the 1st International Workshop on Acute…

The evolving genomic landscape of ALL: molecular genetics, profiling and classification

Acute Lymphoblastic Leukemia 1 Min Read

The genomic analysis of acute lymphoblastic leukemia (ALL) is providing novel insights into the disease, which will inform and direct…

Optimization of standard AML treatment: APL advances, adverse cytogenetics & post-remission therapy

Acute Lymphoblastic Leukemia 1 Min Read

With the excitement surrounding novel therapeutics, reliable conventional treatments can often be overlooked. The optimization of standard treatments is a…

Challenging the norms for elderly AML treatment: clinical trials & intensive therapy

Acute Lymphoblastic Leukemia 1 Min Read

Acute myeloid leukemia (AML) is typically a disease affecting older people, and there are increasing numbers of elderly AML patients…

iwAL 2018: a plethora of new drugs & their impact on trial design

Acute Lymphoblastic Leukemia 1 Min Read

The 1st International Workshop on Acute Leukemias (iwAL), held in St. Pete Beach, FL, was a great success, with the…

Off-the-shelf anti-CD7 CAR T-cells for T-cell malignancies

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cells are a very promising therapeutic for hematological malignancies, with more in development for B-cell compared with T-cell malignancies.…

Immunotherapy for AML and ALL: checkpoint inhibitors & CAR T-cells for B-cell ALL

Acute Lymphoblastic Leukemia 1 Min Read

Immunotherapy is an exciting area, with advocates, sceptics and those who remain undecided without further research. The 1st International Workshop…

Advances in AML understanding: APL therapy, immunotherapy and maintenance therapy

Acute Lymphoblastic Leukemia 1 Min Read

Our understanding of acute myeloid leukemia (AML) has made great strides in recent years, informing the direction of therapeutic strategies.…

MRD for acute leukemias: opinion from both sides of the Atlantic

Acute Lymphoblastic Leukemia 1 Min Read

The 1st International Workshop on Acute Leukemias (iwAL), held in St. Pete Beach, FL, hosted though-provoking discussion on the topic…

iwAL 2018 day 1 discussion: treatment strategies in pediatric and adult ALL

Acute Lymphoblastic Leukemia 1 Min Read

The 1st International Workshop on Acute Leukemias (iwAL), held in St. Pete Beach, FL, hosted an exciting session on treatment…

Acute leukemias: is MRD already a surrogate for survival?

Acute Lymphoblastic Leukemia 2 Mins Read

The use of minimal residual disease (MRD) in the management of acute leukemias is a hotly debated topic. Despite the…

MRD measurement: next-generation sequencing or flow cytometry?

Acute Lymphoblastic Leukemia 1 Min Read

Minimal residual disease (MRD) has become a major tool in the monitoring of hematological malignancies; however, its utility can be…

The rise of MRD in multiple myeloma: could this be an answer to a cure?

Acute Lymphoblastic Leukemia 1 Min Read

Minimal residual disease (MRD) is a hot topic in the world of oncology and many talks on the topic were…

Determining the progression of SMM using predictive biomarkers

Acute Lymphoblastic Leukemia 1 Min Read

Could the progression of smoldering multiple myeloma (SMM) be better predicted? In this interview, Irene Ghobrial, MD, from the Dana-Farber…

Discussing treatment on a global scale: creating a worldwide understanding

Acute Lymphoblastic Leukemia 1 Min Read

The primary focus is often on treatment within the United States or Europe, but what about treatment on a global…

Are there promising treatment options for multiple myeloma on the horizon?

Acute Lymphoblastic Leukemia 1 Min Read

As high-risk patients with multiple myeloma (MM) continue to die from the disease, novel treatments are needed. In this interview,…

What can we learn about CLL by studying environmental stimuli?

Acute Lymphoblastic Leukemia 1 Min Read

Although genetics and epigenetics serve an important role in the efficacy of novel agents such as ibrutinib, other factors must…

Next steps in gaining CLARITY on CLL

Acute Lymphoblastic Leukemia 1 Min Read

With new developments in the treatment of patients with chronic lymphocytic leukemia (CLL), is there a possibility of eradicating the…

An information film to promote informed decision-making for a lung cancer screening

Acute Lymphoblastic Leukemia 1 Min Read

As lung cancer screening is a relatively new area, particularly to non-healthcare professionals, understanding of the procedure and risks involved…

VEGF is Immunomodulatory & Decreases Regulatory T-Cell Responses Significant progress in the field of combining VEGF+TKI with immunotherapy

Acute Lymphoblastic Leukemia 1 Min Read

Tian Zhang, MD Duke University Medical Center, VEGF is Immunomodulatory & Decreases Regulatory T-Cell Responses Significant progress in the field…

Geographic Outcomes of Metastatic RCC in Canada & Europe ESMO-MCBS shows real world data of the availability of new drugs

Acute Lymphoblastic Leukemia 1 Min Read

Aly-Khan Lalani, MD Dana Farber Cancer Institute, discusses Geographic Outcomes of Metastatic RCC in Canada & Europe ESMO-MCBS shows real…

Impact of Geographic Region in Clinical Outcome of Metastatic RCC The overall & progression-free survival seem similar across geographic regions

Acute Lymphoblastic Leukemia 1 Min Read

André P Fay, MD Hospital Mãe De Deus Cancer Institute, discusses Impact of Geographic Region in Clinical Outcome of Metastatic…

Many VEGF Phase 3 Trials Have Completed Accrual Colleagues can visit clinicaltrials.gov to see which are currently accruing

Acute Lymphoblastic Leukemia 1 Min Read

Tian Zhang, MD Duke University Medical Center, discusses Many VEGF Phase 3 Trials Have Completed Accrual Colleagues can visit clinicaltrials.gov…

Physician-Directed Patient-Oriented Improvements How physicians can deliver the best care & cost-intensive but still deliver value

Acute Lymphoblastic Leukemia 1 Min Read

Robert Uzzo, MD Fox Chase Cancer Center, discusses Physician-Directed Patient-Oriented Improvements How physicians can deliver the best care & cost-intensive…

Canada Negotiates Drug Prices w Pan-Canadian Consortium Sunitinib & Pazopanib are most commonly prescribed off trial settings

Acute Lymphoblastic Leukemia 1 Min Read

Aly-Khan Lalani, MD Dana Farber Cancer Institute, discusses Canada Negotiates Drug Prices w Pan-Canadian Consortium Sunitinib & Pazopanib are most…

Early Phase VEGF Trials Enhance Responses in the 1st Line Could lead to improved outcomes of progression-free & overall survival

Acute Lymphoblastic Leukemia 1 Min Read

Tian Zhang, MD Duke University Medical Center, discusses Early Phase VEGF Trials Enhance Responses in the 1st Line Could lead…

Economic Research and Value in Kidney Cancer Value incentivizes provider & delivery of high value quality-based care

Acute Lymphoblastic Leukemia 1 Min Read

Robert Uzzo, MD Fox Chase Cancer Center, discusses Economic Research and Value in Kidney Cancer Value incentivizes provider & delivery…

Sunitinib V. Pazopanib in the First Line Setting Patients receiving sunitinib had better overall survival

Acute Lymphoblastic Leukemia 1 Min Read

Aly-Khan Lalani, MD Dana Farber Cancer Institute, discusses Sunitinib V. Pazopanib in the First Line Setting Patients receiving sunitinib had…

Is Durvalumab (Imfinzi) in Stage III NSCLC Curing Patients or Just Treating Metastatic Disease Earlier? Importance of Overall Survival and Implications for Duration of Treatment (BMIC-025)

Acute Lymphoblastic Leukemia 1 Min Read

Dr. Jack West explores the importance of following the overall survival of patients on the PACIFIC trial and considers still…

Transforming Care After Treatment (TCAT): technology in the delivery of supportive care to lung cancer patients

Acute Lymphoblastic Leukemia 1 Min Read

Following cancer treatment, it is important to support and enable an increasing number of cancer survivors to live as healthy…

Next steps for an innovative electronic holistic care needs assessment tool in Scotland for cancer patients

Acute Lymphoblastic Leukemia 1 Min Read

Following the promising results of initial investigations into the use of an electronic healthcare assessment tool in the delivery of…

Technology in the supportive care of lung cancer patients: patient preference and impact on time efficiency

Acute Lymphoblastic Leukemia 1 Min Read

Integrating technology into healthcare service delivery can improve patient experience whilst improving efficiency. In this interview, Pamela Rose, Macmillan Lung…

APL: getting the perfect picture

Acute Lymphoblastic Leukemia 1 Min Read

Disease monitoring is important to determine what is happening with patients outside of the clinical setting. Speaking from the American…

Targeted treatments for AML: the revolution

Acute Lymphoblastic Leukemia 1 Min Read

Exciting advancements in acute myeloid leukemia (AML) research were discussed during the American Society of Hematology (ASH) 2017 Annual Meeting…

Advancements in APL treatment: oral ATO, MRD and treatment objectives

Acute Lymphoblastic Leukemia 1 Min Read

Despite the remarkable progress being made in the treatment of patients with acute promyelocytic leukemia (APL), a high rate of…

Novel ALL treatment strategies: CAR T-cells

Acute Lymphoblastic Leukemia 1 Min Read

CAR T-cells are a universally exciting area in hematological oncology. Speaking from the American Society of Hematology (ASH) 2017 Annual…

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