In this video, Dominique Bonnet, PhD, of the Francis Crick Institute, London, UK, outlines her group’s research into the biology of leukemia. Dr Bonnet explains how they overcame the limitations of studying human cells and disease in murine environments, and the many different applications that this technology can have once it’s fully developed. This interview was recorded at the 2018 European School of Hematology (ESH) Clinical Updates on Acute Leukemias, held in Budapest, Hungary.