Martine Bagot, MD, PhD, of Saint Louis Hospital, Paris, France, discusses the exciting new approval of the antibody mogumulizumab for cutaneous T-cell lymphoma. Speaking at the European Organisation for the Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Task Force (CLTF) 2018 Congress, held in St. Gallen, Switzerland, she presents two case studies of patients who developed autoimmunity, where they entered complete remission for a significant period of time after receiving injections of this antibody. Prof. Bagot is excited about the therapy and accounts the antibodies successful response to its potential mechanism of regulatory T-cell depletion.