In this interview, Raúl Córdoba, MD, PhD, MS, of the Fundacion Jimenez Diaz University Hospital, Madrid, Spain, discusses the problems facing clinicians in the treatment of elderly patients with lymphoma. Dr Córdoba then describes ways to improve patient treatment, including stratification based on their fitness and the use of different treatment modalities, such as CAR T-cell and other immunotherapeutic approaches. This video was recorded at the American Society of Oncology (ASCO) 2018 Annual Meeting, held in Chicago, IL.