Exciting clinical trial updates were presented at the British Thoracic Oncology Group (BTOG) Annual Conference 2018, held in Dublin, Ireland. Speaking from the meeting, Robert Rintoul, PhD, FRCP, of the Cancer Research UK Cambridge Institute, Cambridge, UK, discusses the updates that he presented on the MARS2 (NCT02040272) and MesoTRAP (NCT03412357) studies for mesothelioma. MARS2 is investigating whether pleurectomy/decortication confers a survival advantage, whereas MesoTRAP is a feasibility study comparing pleurectomy/decortication vs. indwelling pleural catheter treatment for trapped lung. Dr Rintoul gives an overview of the progress of the trials thus far, as well as the additional measurements being incorporated, including health economics and QuinteT recruitment intervention.