Kinase inhibitors are one of the most successful forms of therapy for hematological malignancies, with further potential due to new advances. Speaking from the 1st European Myeloma Network Meeting (EMN) in Turin, Italy, Fabio Malavasi, MD, of the University of Turin, Turin, Italy, describes some of the work currently being performed regarding predictive biomarkers for kinase inhibitor treatment response. Prof. Malavasi also mentions daratumumab and its synergistic action when given to patients in combination with novel kinase inhibitors.