The results of clinical trials are open to interpretation and are dependent upon a vast array of factors, including cohort size, the endpoints chosen and the statistics used to analyze the resulting date. Here, Robert Hills from the University of Oxford, Oxford, UK, discusses the most important considerations when judging the value of a clinical trial. This video was recorded at the European School of Haematology (ESH) International Conference on MM 2018, held in Mandelieu, France.