Catherine Bollard, MBChB, MD, FRACP, FRCPA from the Childrens National Health System and the George Washington University, Washington, D.C. chairs a lively discussion on the fast-evolving field of immunotherapy in lymphoma. Dr Bollard is joined by Stephan Ansell, MD, PhD from the Mayo Clinic, MN and Steve Gottschalk, MD from the Baylor College of Medicine, Houston, TX, together they review the immunotherapy session at the 2017 International Workshop on Non-Hodgkin Lymphoma (iwNHL) in Vancouver, BC, Canada. It is an exciting time in lymphoma, with immunotherapies such as CAR T-cells and checkpoint inhibitors showing promising results. Discussing how these could be used in combination, the experts also consider the current challenges in this field.