At the British Society for Haematology (BSH) 2018 Annual Scientific Meeting, held in Liverpool, UK, Anita Hill, MBChB (Hons), MRCP, FRCPath, PhD, from Leeds Teaching Hospital NHS Trust, Leeds, UK, discusses possible new diagnostic indicators to detect thrombosis in patients with paroxysmal nocturnal hemoglobinuria (PNH). Studies are investigating the mechanisms of thrombosis and how to use features of this as indicative markers, such as those in the coagulation cascade, including fibrinogen and platelet levels.