The future of biology is becoming increasingly technologically-based. In this video, Dominique Bonnet, PhD, of the Francis Crick Institute, London, UK, begins by emphasizing the need for bioinformaticians in her own laboratory, as much of her research requires mathematical analysis, before continuing to speak about the applications of these new analytic methods in her current research, which involves tracking leukemic cell migration in murine models. Dr Bonnet mentions how stem cells are often overlooked when analyzing samples, as they do not always match the classical round, undifferentiated appearance, but instead have different morphologies, including filopodia, before concluding her interview by stating some of the questions her group is seeking to answer in relation to these stem cells and the biology of leukemia itself. This interview was recorded at the 2018 European School of Hematology (ESH) Clinical Updates on Acute Leukemias, held in Budapest, Hungary.