Chirag Shah, MD, Director of Breast Radiation Oncology and Director of Clinical Research in the Department of Radiation Oncology at Cleveland Clinic. In this video, he speaks about the Miami Breast 2022 Abstract - Medical Crossfire®: PRO vs CON: Breast IORT Is the Preferred Accelerated Breast Treatment Option.
Intraoperative radiotherapy (IORT) is a form of accelerated partial breast irradiation (APBI) in which radiation therapy is provided to the breast tissue during a lumpectomy for breast cancer in a single dose. The Xoft device (Axxent, Xoft, San Jose, CA) is an IORT device for breast cancer that uses kilovoltage (kV) photons. The primary purpose of this study is to report on acute and late toxicities, as well as cosmetic outcomes, after breast IORT with the Xoft device in women with early-stage breast cancer treated with lumpectomy. The researchers believe that IORT after a lumpectomy will be safe and well-tolerated, with a lower rate of physician-reported acute adverse effects than standard whole breast radiation therapy after a lumpectomy.