At the 2014 American Society of Hematology (ASH) Annual Meeting, Dr Catherine Bollard (Children’s National Medical Center, Washington, DC), Dr Philippe Armand (Dana-Farber Cancer Institute, Boston, MA), Dr Craig Moskowitz (Memorial Sloan Kettering Cancer Center, New York, NY), Dr Nicola Gökbuget (University Hospital Frankfurt, Frankfurt, Germany) and Dr Stephan Grupp (Children’s Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA) answer questions from the press.