Denis Claude Roy, MD, FRCP, of the University of Montreal, Montreal, Canada, is involved in developing a technique for eradicating the risk of GvHD in haploidentical stem cell transplant recipients by selectively killing the donor cells that react to host cells. In this video, recorded at the 2018 European Society for Blood and Marrow Transplantation (EBMT) Annual Meeting in Lisbon, Portugal, he discusses the wide-reaching potential for this technology, as well as considerations for donor matching.