In this video, Elizabeth Plimack, MD, from Fox Chase Cancer Center, Philadelphia, PA, discusses the progress made in prostate, bladder and kidney cancer. There have been significant advances in immunotherapeutic options, particularly for the treatment of bladder and kidney cancers. Speaking from the 2018 Genitourinary Cancers Symposium, held in San Francisco, CA, Dr Plimack mentions the challenges to overcome with non-responders and the different combinations that can be tested, particularly those including checkpoint inhibitors.