T cells targeting multiple tumor-associated antigens in lymphoma

At the 58th American Society of Hematology (ASH) Annual Meeting & Exposition, Catherine Bollard, MBChB, MD, FRACP, FRCPA, from Children’s National Medical Center, Washington, DC, discusses the development of a protocol for the generation of single T-cell lines that simultaneously target a range of tumor-associated antigens that are frequently expressed in tumours of individuals with Hodgkin lymphoma or non-Hodgkin lymphoma, including PRAME, SSX2, MAGEA4, NY-ESO-1 and Survivin.