Anne S. Tsao, MD of MD Anderson Cancer Center discusses third generation TKIs and how they cause less diarrhea, abdominal issues, skin rashes, and provide higher quality of life. However, doctors might need to watch out with Osimertinib and get baseline EKG and echo. In this way, QTc prolongation can be known. Patients also should be checked if they have concomitant medication that can cause QTc prolongation which can occur in minor group of patients. However, since Osimertinib crosses the blood brain barrier it is a associated with a very good quality of life.
Third Generation TKIs Less Diarrhea, Abdominal Issues, Rash, & Improved Life
