Daniel A. Pryma, MD of the University of Pennsylvania discusses how fluorodeoxyglucose (FDG) PET scan is still powerful tool for lung cancer. Both for non-small and small cell lung cancer, the FDG is still the most powerful imaging tool. Although there are ongoing researches in PET CT with different radiopharmaceuticals, but for lung cancer, FDG still remains the mainstay and the most accurate. From different targeted therapies, it is anticipated that there may be other agents, but, for the time being, FDG is still the most important and the most effective.