Patient reported outcomes (PROs) are reports that can provide insightful information from patients, including how they feel about their condition and the therapies that are being used for treatment. Here, Freddie Hamdy, MBChB, LRCSPEd, LRCSEd, LRCPSGlasg, FRCSEd, MD, FRCSEd(Urol), FRCS, FMedSci, of the University of Oxford, Oxford, UK, presents the PROs from the ProtecT trial (NCT02044172), a study that compared the effectiveness of active monitoring, radical prostatectomy and radiotherapy in patients with localized prostate cancer. Dr Hamdy emphasizes the importance of utilizing PROs when counselling patients on treatment options. This interview was recorded at the 2017 National Cancer Research Institute (NCRI) Conference in Liverpool, UK.