Here, Jacob Kettle, PharmD, BCOP, of the University of Missouri Health Care, Columbia, MO, shares his perspective on the different challenges surrounding the advancements made in the development of newer immunotherapy agents for pharmacists, including the need to constantly keep up to date with newly approved drugs, and being aware of their side effects on different organ systems upon administration. This video was recorded at the 2018 Hematology/Oncology Pharmacy Association (HOPA) Annual Conference held in Denver, CO.